Product image of Nizonide (Nitazoxanide) 500 mg Tablet supplied by GNH India

Nizonide

Active Ingredient:
Nitazoxanide
Form:
Tablet
Brand:
Nizonide 500
Origin:
India

Nizonide (Nitazoxanide Tablet) 500 mg

Nitazoxanide, the active ingredient in Nizonide 500, is a thiazolide presented as a 500 mg tablet for oral use. It is used to treat parasitic infections, including diarrhea caused by protozoa such as Cryptosporidium and Giardia. GNH India supplies Nizonide 500 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Nizonide 500 is an antiprotozoal medication that effectively targets and inhibits the growth of parasites responsible for various infections. It is widely recognized for its efficacy in managing diarrhea and worm infections, providing relief and preventing recurrence.

Strength

500 mg

Pack Size

60s

Storage

Ambient

Manufacturer / TM Owner

IND-SWIFT Ltd

1
Pack/s
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Indications & Clinical Uses

Nizonide 500 is an antiprotozoal medication used to treat infections caused by parasites. It is particularly effective in managing the following conditions:

  • Cryptosporidiosis: Treats diarrhea caused by the Cryptosporidium parasite.
  • Giardiasis: Effective against Giardia infections, which can cause gastrointestinal issues.
  • Diarrhea: Helps manage diarrhea caused by parasitic infections, ensuring hydration and relief from frequent loose motions.
  • Worm infections: Inhibits the growth of parasitic worms, preventing further infection and promoting recovery.

How It Works

  • Nitazoxanide, the active ingredient in Nizonide 500, works by inhibiting the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction. This process is essential for the anaerobic metabolism of protozoa and some bacteria, effectively stopping the growth and reproduction of these parasites.

Side Effects

Nizonide 500 may cause several side effects, ranging from mild to severe. It is important to be aware of these potential reactions.

Common Side Effects

  • Headache: May occur during the course of treatment.
  • Abdominal pain: Some patients may experience discomfort in the abdominal area.
  • Nausea: A common gastrointestinal side effect.
  • Chromaturia: Changes in urine color may be observed.

Serious or Rare Side Effects

  • Allergic reactions: Rare but can include rash, itching, or swelling.
  • Severe diarrhea: Persistent or worsening diarrhea should be reported to a healthcare provider.
  • Liver dysfunction: Monitor liver function tests if symptoms of liver issues arise.

Precautions & Warnings

Nizonide 500 should be used with caution and under the supervision of a healthcare provider. Important precautions include:

  • Pregnancy: Consult your doctor before taking Nizonide 500 during pregnancy.
  • Breastfeeding: Use with caution and monitor the baby for any adverse effects.
  • Medical conditions: Inform your doctor about any existing medical conditions.
  • Drug interactions: Let your doctor know about all medications you are taking.
  • Driving: Avoid driving if you experience dizziness or drowsiness.
  • Storage: Store at 20° to 25°C: Keep in a cool, dry place, protect from light and moisture.

Avoid Interactions

Nizonide 500 may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. It is crucial to be aware of these interactions.

Major Interactions (Avoid)

  • Antacids: May reduce the absorption of Nizonide 500.
  • Anticoagulants: Potential for increased bleeding risk.

Moderate Interactions (Monitor Closely)

  • Antiepileptics: May alter the effectiveness of Nizonide 500.
  • Antifungals: Potential for increased side effects.
  • Antibiotics: May require dose adjustments or close monitoring.

Frequently Asked Questions

Nizonide 500 is used to treat parasitic infections, including diarrhea caused by protozoa such as Cryptosporidium and Giardia. It is also effective against worm infections, helping to inhibit the growth of parasites and promote recovery.

Nitazoxanide, the active ingredient in Nizonide 500, works by inhibiting the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction. This process is essential for the anaerobic metabolism of protozoa and some bacteria, effectively stopping the growth and reproduction of these parasites.

The dose of Nizonide 500 should be determined by a healthcare provider based on the patient's condition, age, and other factors. It is important to follow the prescribed dosage and complete the full course of treatment.

Nizonide 500 is generally considered safe to use during pregnancy. However, it is important to consult your doctor before taking any medication while pregnant to ensure safety and appropriate dosage.

To order Nizonide 500 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Nizonide 500 is effective against a range of parasitic infections, including Cryptosporidium and Giardia. Compared to other antiprotozoal medications, it is known for its broad-spectrum activity and relatively mild side effect profile. However, the choice of medication should be based on the specific infection and the patient's medical history.

Nizonide 500 should be stored at 20° to 25°C in a cool, dry place, protected from light and moisture. Ensure the medication is kept out of reach of children and in its original packaging.

Nizonide 500 is administered orally, typically with food, to enhance absorption and reduce the risk of gastrointestinal side effects. It is important to follow the prescribed dosage and complete the full course of treatment as directed by your healthcare provider.

The most serious risks associated with Nizonide 500 include severe allergic reactions, persistent or worsening diarrhea, and liver dysfunction. Patients should be monitored for these side effects and report any adverse reactions to their healthcare provider immediately.

Nizonide 500 should not be used by individuals who are allergic to Nitazoxanide or any of the other ingredients in the medication. Patients with severe liver disease or those taking certain medications that interact with Nizonide 500 should also avoid using it unless directed by a healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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