Product image of Nizoral (Ketoconazole) supplied by GNH India

Nizoral

Active Ingredient:
Ketoconazole
Origin:
EU

Nizoral (Ketoconazole)

Ketoconazole, the active ingredient in Nizoral, is an imidazole antifungal presented as a topical formulation for skin use. It treats a variety of superficial fungal infections in adults and children.

GNH India supplies Nizoral as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality and regulatory compliance.

Manufacturer / TM Owner

Stada Arzneimittel Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ketoconazole is used topically to treat fungal skin conditions by targeting dermatophyte and yeast infections.

  • Athlete's foot (tinea pedis): reduces itching and clears infection
  • Jock itch (tinea cruris): alleviates redness and eliminates fungal growth
  • Ringworm (tinea corporis): promotes healing of circular lesions
  • Seborrheic dermatitis: controls flaking and erythema on scalp and face
  • Pityriasis versicolor: restores normal skin pigmentation

How It Works

  • Ketoconazole inhibits the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. Disruption of ergosterol production compromises the integrity of the fungal cell membrane, leading to increased permeability and ultimately cell death. This targeted action limits fungal growth on the skin surface.

Side Effects

Topical ketoconazole may cause local skin reactions and, rarely, systemic adverse events.

Common Side Effects

  • Itching: mild to moderate pruritus at the application site
  • Burning sensation: transient heat feeling
  • Redness: localized erythema
  • Dryness: skin becomes flaky
  • Scaling: slight desquamation
  • Contact dermatitis: mild allergic response

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or anaphylaxis
  • Skin ulceration: breakdown of the epidermis
  • Photosensitivity: increased sunburn risk
  • Systemic toxicity: liver enzyme elevation with extensive use
  • Stevens‑Johnson syndrome: rare mucocutaneous blistering

Precautions & Warnings

When using topical ketoconazole, consider the following safety measures.

  • Avoid use on broken skin: may increase systemic absorption
  • Do not apply near eyes or mucous membranes: risk of irritation
  • Check for hypersensitivity: discontinue if rash develops
  • Limit treatment duration: typically 2–4 weeks unless directed
  • Consult physician before combining with other topical agents: potential irritation
  • Store at room temperature: keep in original container, protect from moisture and light

Avoid Interactions

Ketoconazole can interact with certain medications and treatments.

Major Interactions (Avoid)

  • Concurrent oral ketoconazole therapy: duplicate antifungal effect and increased toxicity
  • Use with systemic CYP3A4 inhibitors (e.g., itraconazole, erythromycin): may raise systemic ketoconazole levels
  • Co‑application with other potent topical antifungals: risk of excessive irritation

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask signs of irritation
  • Phototherapy (UV light): can enhance skin sensitivity
  • Other hepatotoxic drugs (e.g., high‑dose acetaminophen): monitor liver function if extensive absorption occurs

Frequently Asked Questions

Nizoral contains ketoconazole and is applied to the skin to treat superficial fungal infections such as athlete's foot, jock itch, ringworm, seborrheic dermatitis, and pityriasis versicolor. It works by eliminating the fungi that cause these conditions.

Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for producing ergosterol, a key component of fungal cell membranes. Without ergosterol, the membrane becomes unstable, leading to fungal cell death and clearance of the infection.

The prescribed amount of Nizoral is determined by a healthcare professional based on the infection type, severity, and patient age. Typically, a thin layer is applied to the affected area once or twice daily for a period recommended by the prescriber.

Safety data for topical ketoconazole during pregnancy or lactation are limited. Healthcare providers usually weigh potential benefits against risks before prescribing it to pregnant or nursing individuals. Patients should discuss any concerns with their clinician.

To order Nizoral, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nizoral (ketoconazole) belongs to the imidazole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, ketoconazole has a slightly slower onset but is effective for a wide range of skin infections and is available in a convenient topical form.

Store Nizoral at room temperature, preferably below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Handle with clean hands and avoid contaminating the tube tip.

Clean and dry the affected skin area before use. Apply a thin, even layer of Nizoral to the lesion and a small margin of surrounding skin. Gently rub it in until it disappears, and wash hands after application unless the hands are being treated.

Although uncommon, serious reactions can include severe allergic responses such as swelling, hives, or anaphylaxis, as well as skin ulceration and rare systemic effects like liver enzyme elevation. If any of these occur, stop using the product and seek medical attention promptly.

Individuals with known hypersensitivity to ketoconazole or any component of the formulation should avoid Nizoral. It is also contraindicated on extensive broken skin, mucous membranes, or in patients who are simultaneously using oral ketoconazole without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ketoconazole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT