Nizoral (Ketoconazole)

Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for synthesising ergosterol, a key component of the fungal cell membrane. Without ergosterol, the membrane becomes leaky, leading to fungal cell death and clearance of the infection.

The specific dose and frequency of Nizoral are determined by the prescribing healthcare professional based on the type and severity of the infection, the patient’s age, and other clinical factors. Patients should follow the prescriber’s instructions exactly.

Safety data for topical ketoconazole in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nizoral.

To order Nizoral, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nizoral (ketoconazole) belongs to the azole class, which is effective against a broad range of dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, azoles have a broader spectrum but may carry a higher risk of hepatic interaction when absorbed systemically.

Nizoral should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Nizoral is applied topically to the affected skin area, usually once or twice daily as directed by a healthcare professional. The skin should be clean and dry before application, and the medication should be gently rubbed in until fully absorbed.

Although rare, serious risks include systemic hepatotoxicity, severe allergic reactions such as anaphylaxis, and rare severe skin reactions like Stevens‑Johnson syndrome. Any signs of liver dysfunction, widespread rash, or difficulty breathing should prompt immediate medical attention.

Individuals with known hypersensitivity to ketoconazole or any component of the formulation should avoid Nizoral. Patients with extensive broken skin, severe liver disease, or those taking interacting systemic medications should consult a healthcare professional before use.