Nizoral (Ketoconazole)

Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, preventing the synthesis of ergosterol, an essential component of the fungal cell membrane. This disruption compromises membrane integrity, leading to fungal cell death while sparing human cells.

The specific dose and frequency of Nizoral are determined by the prescribing healthcare professional based on the infection type, severity, patient age and other clinical factors. Patients should follow the prescriber’s instructions exactly.

Safety of ketoconazole topical use in pregnancy or lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nizoral.

To request Nizoral, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoconazole belongs to the azole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, ketoconazole may have a slightly slower onset but is effective for a wide range of skin and scalp infections, especially those involving Malassezia species.

Store Nizoral below 25 °C in its original packaging, protecting it from moisture, heat and direct sunlight. Ensure the container is tightly closed to maintain product stability throughout its shelf life.

Apply a thin layer of the cream to the affected skin area once or twice daily, as directed by the prescriber. Gently massage until fully absorbed, and wash hands after application to avoid accidental contact with eyes or mucous membranes.

Although rare, serious adverse reactions can include severe allergic responses such as swelling, hives, or difficulty breathing, and systemic effects like hepatotoxicity if significant absorption occurs. Immediate medical attention is required if these symptoms develop.

Nizoral should not be used on broken or severely inflamed skin, in individuals with known hypersensitivity to ketoconazole or any formulation component, and it is contraindicated when occlusive dressings are applied over the treated area without medical supervision.