Nizoral (Ketoconazole)

Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for producing ergosterol, a key component of the fungal cell membrane. Without ergosterol, the membrane becomes defective, leading to fungal cell death and resolution of the infection.

The specific dose and frequency of Nizoral are determined by the prescribing healthcare professional based on the infection type, severity, patient age, and treatment guidelines. Patients should follow the prescriber’s instructions and the product label carefully.

Safety data for topical ketoconazole in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nizoral.

To order Nizoral, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoconazole is an imidazole antifungal that offers broad‑spectrum activity against yeasts and dermatophytes. Compared with allylamine agents such as terbinafine, ketoconazole is often chosen for its efficacy on Malassezia species and for topical formulations that are convenient for scalp and skin use.

Nizoral should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Apply a thin layer of the topical product to the affected skin or scalp once or twice daily, as directed by the prescriber. Gently massage it into the skin until it is absorbed, and wash hands after application unless the hands are being treated.

Serious risks, though rare with topical use, include severe allergic reactions such as angioedema, Stevens‑Johnson syndrome, and systemic liver toxicity if significant absorption occurs. Patients should seek immediate medical attention if they notice widespread rash, swelling, or signs of liver dysfunction.

Individuals with known hypersensitivity to ketoconazole or any component of the formulation should avoid Nizoral. It is also contraindicated on severely damaged, inflamed, or ulcerated skin, and should be used with caution in children under 12 years of age unless advised by a clinician.