Product image of Noctis Noc (Doxylamine Hydrogen Succinate) supplied by GNH India

Noctis Noc

Active Ingredient:
Doxylamine Hydrogen Succinate
Origin:
EU

Noctis Noc (Doxylamine Hydrogen Succinate)

Doxylamine, the active ingredient in Noctis Noc, is a first‑generation H1 antihistamine presented as an oral tablet for oral use. It is employed to alleviate short‑term insomnia and to relieve allergic symptoms such as rhinitis and urticaria in adults.

GNH India supplies Noctis Noc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent batch release, comprehensive documentation, and responsive technical support.

Manufacturer / TM Owner

Biofarm Sp. Z O.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Doxylamine acts on histamine H1 receptors to provide sedative and antihistaminic effects.

  • Insomnia: helps initiate and maintain sleep in adults with short‑term difficulty.
  • Allergic rhinitis: reduces nasal congestion, itching and sneezing associated with seasonal allergies.
  • Urticaria: alleviates itching and hives caused by allergic reactions.

How It Works

  • Doxylamine is a competitive antagonist of peripheral H1 histamine receptors and penetrates the central nervous system where it blocks H1 receptors, producing sedation. It also exhibits anticholinergic activity by inhibiting muscarinic receptors, contributing to its hypnotic and anti‑allergic properties. The combined peripheral and central actions reduce the effects of histamine release, leading to decreased allergic symptoms and promotion of normal sleep.

Side Effects

Doxylamine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Drowsiness
  • Dry mouth
  • Blurred vision
  • Constipation

Serious or Rare Side Effects

  • Anaphylaxis
  • Severe cardiac arrhythmia
  • Seizures
  • Hallucinations

Precautions & Warnings

When using Noctis Noc, consider the following precautions:

  • Pregnancy: consult a healthcare professional before use.
  • Elderly: increased sensitivity to sedative effects.
  • Operating machinery: avoid driving or operating equipment until effects are known.
  • Alcohol: avoid concurrent consumption due to additive CNS depression.
  • Medical conditions: use cautiously in glaucoma, urinary retention, or COPD.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Doxylamine can interact with several medicines; review the categories below.

Major Interactions (Avoid)

  • Alcohol: additive sedation and respiratory depression.
  • Opioids: enhanced CNS depression and risk of respiratory compromise.
  • Other CNS depressants (benzodiazepines, barbiturates): increased drowsiness and impaired coordination.
  • Anticholinergic drugs: cumulative anticholinergic burden may cause severe dry mouth, urinary retention.

Moderate Interactions (Monitor Closely)

  • Antihistamines (second‑generation): additive sedation.
  • CYP2D6 inhibitors (e.g., fluoxetine): may increase plasma levels of doxylamine.
  • Tricyclic antidepressants: additive anticholinergic effects.
  • SSRIs: potential for increased sedation.

Frequently Asked Questions

Noctis Noc contains doxylamine, which is used for short‑term treatment of insomnia and for relief of allergic symptoms such as rhinitis and urticaria. It helps people fall asleep and reduces itching, sneezing, and hives associated with allergic reactions.

Doxylamine works by competitively blocking H1 histamine receptors in both peripheral tissues and the central nervous system. This antagonism reduces the actions of histamine that cause allergy symptoms and also produces a sedative effect that promotes sleep.

The appropriate dose of Noctis Noc is determined by a qualified healthcare professional based on the individual’s age, condition, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety information for doxylamine in pregnancy and lactation is limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their doctor before using Noctis Noc.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both doxylamine and diphenhydramine are first‑generation antihistamines with sedative properties. Doxylamine generally has a longer half‑life, which may provide more sustained sleep support, while diphenhydramine may wear off earlier. Individual response varies, so clinicians choose the agent that best fits the patient’s needs.

Store Noctis Noc at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture, direct sunlight and excessive heat to maintain potency.

Noctis Noc is taken orally, usually with a full glass of water. It is intended for short‑term use, and patients should follow the timing and dosing instructions provided by their prescriber.

Serious adverse reactions, although rare, include anaphylaxis, severe cardiac arrhythmias, seizures, and hallucinations. Anyone experiencing these symptoms should seek immediate medical attention.

Individuals with known hypersensitivity to doxylamine or other first‑generation antihistamines, patients with severe glaucoma, urinary retention, or uncontrolled asthma, and those taking certain CNS depressants should avoid Noctis Noc unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.