Product image of Noctor (Diphenhydramine Hydrochloride) supplied by GNH India

Noctor

Active Ingredient:
Diphenhydramine Hydrochloride
Origin:
EU

Noctor (Diphenhydramine Hydrochloride)

Diphenhydramine Hydrochloride, the active ingredient in Noctor, is a first‑generation antihistamine presented as an oral dosage form for oral use. It treats allergic rhinitis, urticaria, pruritus and short‑term insomnia in appropriate patient groups.

GNH India supplies Noctor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wabosan Arzneimittelvertriebs Gmbh

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Indications & Clinical Uses

Diphenhydramine acts on histamine‑mediated allergic conditions and related symptoms.

  • Allergic rhinitis: reduces nasal congestion, sneezing and itching.
  • Urticaria and other allergic skin reactions: diminishes hives and associated itching.
  • Pruritus: provides relief from generalized itching.
  • Insomnia (short‑term use): induces drowsiness to aid sleep.

How It Works

  • Diphenhydramine Hydrochloride competitively antagonises histamine H1 receptors in peripheral tissues and the central nervous system, preventing histamine‑induced vasodilation, increased vascular permeability and sensory nerve stimulation, thereby alleviating allergic symptoms and producing sedative effects.

Side Effects

Adverse reactions may occur with diphenhydramine use.

Common Side Effects

  • Drowsiness: feeling of sleepiness or reduced alertness.
  • Dry mouth: decreased salivary flow.
  • Blurred vision: temporary visual disturbance.
  • Constipation: reduced bowel movements.
  • Urinary retention: difficulty emptying the bladder.
  • Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects

  • Tachycardia: rapid heart rate.
  • Anaphylaxis: severe allergic reaction with airway compromise.
  • Confusion or hallucinations: altered mental status.
  • Seizures: uncontrolled electrical activity in the brain.
  • Cardiac arrhythmias: irregular heart rhythm.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.

Precautions & Warnings

When using Noctor, consider the following safety measures.

  • Pediatric use: follow prescriber guidance due to heightened sedation risk.
  • Operating machinery: avoid driving or using heavy equipment while impaired.
  • Glaucoma: anticholinergic effects may exacerbate intra‑ocular pressure.
  • Hepatic impairment: reduced metabolism may increase drug exposure.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Diphenhydramine may interact with several medicines.

Major Interactions (Avoid)

  • Alcohol: additive central nervous system depression.
  • MAO inhibitors: risk of hypertensive crisis.
  • Sedatives (e.g., benzodiazepines, opioids): enhanced sedation.

Moderate Interactions (Monitor Closely):\n- CYP2D6 inhibitors (e.g., fluoxetine): may increase diphenhydramine levels.

  • Antacids: can affect oral absorption.
  • Antihypertensives: possible additive hypotensive effect.

Frequently Asked Questions

Noctor contains diphenhydramine Hydrochloride, an over‑the‑counter antihistamine indicated for relief of allergic rhinitis, urticaria, other allergic skin reactions, pruritus and short‑term insomnia when used as directed by a healthcare professional.

Diphenhydramine works by competitively blocking histamine H1 receptors in the body, preventing histamine from binding and triggering the cascade that leads to itching, swelling, redness and the wake‑promoting effects of histamine in the brain.

The appropriate dose of Noctor is determined by the prescribing clinician based on the patient’s age, weight, condition being treated and any other relevant medical factors. Patients should follow the prescriber’s instructions and the product label.

Safety data for diphenhydramine in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and always under the guidance of a qualified healthcare professional.

To order Noctor, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Noctor (diphenhydramine) is a first‑generation antihistamine that causes sedation and anticholinergic effects, whereas second‑generation agents such as cetirizine or loratadine are less sedating and have a lower risk of anticholinergic side effects. Choice depends on the clinical situation and patient tolerance.

Store Noctor at temperatures below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date printed on the label.

Noctor is taken orally. Swallow the tablet whole with a glass of water; it may be taken with or without food. Follow the prescriber’s dosing schedule and do not exceed the recommended amount.

Serious risks include severe allergic reactions such as anaphylaxis, cardiac arrhythmias, tachycardia, confusion, hallucinations, seizures and, in rare cases, life‑threatening skin reactions. Seek immediate medical attention if any of these symptoms develop.

Noctor should be avoided by individuals with known hypersensitivity to diphenhydramine or any formulation components, newborns, patients with severe asthma, narrow‑angle glaucoma, or those taking contraindicated medications such as MAO inhibitors. A healthcare professional should evaluate suitability before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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