Product image of Nogrip (Pheniramine Maleate, Ascorbic Acid, Paracetamol) supplied by GNH India

Nogrip

Active Ingredient:
Pheniramine Maleate, Ascorbic Acid, Paracetamol
Origin:
EU

Nogrip (Pheniramine Maleate, Ascorbic Acid, Paracetamol)

Pheniramine maleate, the active ingredient in Nogrip, is an H1‑receptor antagonist presented as an oral formulation for symptomatic relief of allergic rhinitis, headache, fever and common cold in adults and children. The product also contains paracetamol for analgesic and antipyretic action and ascorbic acid as an antioxidant, supporting overall symptom management.

GNH India supplies Nogrip as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, ensuring quality and regulatory compliance across multiple markets through robust quality‑assured manufacturing and reliable distribution networks.

Manufacturer / TM Owner

Dr. Max Pharma S.R.O.

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Indications & Clinical Uses

Nogrip combines an antihistamine, an analgesic/antipyretic and vitamin C, acting on allergic and inflammatory pathways to relieve common cold‑related symptoms.

  • Allergic rhinitis: reduces nasal congestion, itching and sneezing.
  • Common cold: alleviates runny nose, sore throat and general malaise.
  • Headache: provides analgesic relief of tension‑type headache.
  • Fever: lowers elevated body temperature associated with viral infections.

How It Works

  • Pheniramine maleate blocks H1 histamine receptors, preventing the actions of histamine that cause itching, swelling and vasodilation. Paracetamol inhibits central cyclooxygenase enzymes, reducing prostaglandin synthesis to produce analgesic and antipyretic effects. Ascorbic acid functions as an antioxidant and cofactor in metabolic pathways, supporting immune function and tissue repair.

Side Effects

Adverse reactions to Nogrip may vary in frequency and severity.

Common Side Effects

  • Drowsiness: mild sedation or sleepiness.
  • Dry mouth: reduced salivary flow causing throat discomfort.
  • Nausea: upset stomach or feeling of queasiness.
  • Dizziness: light‑headed sensation, especially on standing.
  • Headache: mild to moderate head pain.
  • Gastrointestinal upset: mild abdominal discomfort.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with rash, swelling and breathing difficulty.
  • Hepatotoxicity: liver injury from excessive paracetamol exposure.
  • Blood disorders: rare cases of thrombocytopenia or neutropenia.

Precautions & Warnings

When considering Nogrip, several precautionary measures should be observed.

  • Assess liver function: evaluate hepatic status before use due to paracetamol content.
  • Limit alcohol intake: avoid concurrent excessive alcohol to reduce liver risk.
  • Use caution in renal impairment: adjust dose or monitor if kidney disease is present.
  • Avoid in children under 12 years: not recommended without medical advice.
  • Pregnant or breastfeeding women: consult a healthcare professional before use.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Nogrip can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Warfarin: paracetamol may increase anticoagulant effect and INR.
  • Other hepatotoxic drugs (e.g., isoniazid, methotrexate): additive risk of liver injury.
  • Heavy alcohol consumption: markedly raises risk of hepatic toxicity.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines, opioids): may enhance sedation.
  • Additional antihistamines: can cause additive anticholinergic effects.
  • CYP450 substrates: paracetamol metabolism may alter levels of drugs processed by CYP2E1.

Frequently Asked Questions

Nogrip is formulated to provide symptomatic relief of allergic rhinitis, common cold, headache and fever. It combines an antihistamine, an analgesic/antipyretic and vitamin C to address nasal congestion, sneezing, sore throat, pain and elevated body temperature associated with viral upper‑respiratory infections.

Pheniramine maleate is an H1‑receptor antagonist. By binding to histamine H1 receptors on mast cells and other tissues, it blocks the actions of histamine that cause itching, swelling, vasodilation and increased mucus production, thereby reducing the classic symptoms of allergic reactions.

The appropriate dose of Nogrip is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and any concomitant therapies. Patients should follow the prescriber’s instructions and the product label without altering the regimen on their own.

Safety of Nogrip in pregnancy or lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using the product.

To place an order, submit an enquiry on the Nogrip product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike single‑ingredient decongestants, Nogrip offers a multi‑component approach: an antihistamine for allergic symptoms, paracetamol for pain and fever, and vitamin C for antioxidant support. This combination can simplify therapy by reducing the need for multiple separate products, while still addressing the key symptoms of a common cold.

Nogrip should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool place helps maintain its stability and potency throughout its shelf life.

Nogrip is intended for oral use. The tablet (or other oral dosage form) should be swallowed whole with a glass of water, unless otherwise directed by a healthcare professional. It is usually taken with or without food, as advised by the prescriber.

The most serious risks include severe allergic reactions such as anaphylaxis, and liver injury from excessive paracetamol exposure, especially when combined with alcohol or other hepatotoxic drugs. Patients should seek immediate medical attention if they experience rash, swelling, breathing difficulty, jaundice or unexplained fatigue.

Individuals with known hypersensitivity to pheniramine, paracetamol, ascorbic acid or any excipients should avoid Nogrip. It is also contraindicated in patients with severe liver disease, uncontrolled asthma triggered by antihistamines, or in children for whom the dosage has not been established without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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