Product image of Nomegestrol Stragen (Nomegestrol Acetate) supplied by GNH India

Nomegestrol Stragen

Active Ingredient:
Nomegestrol Acetate
Origin:
EU

Nomegestrol Stragen (Nomegestrol Acetate)

Nomegestrol acetate, the active ingredient in Nomegestrol Stragen, is a synthetic progestogen presented as an oral tablet for oral use. It is employed in hormonal contraception, the management of menstrual disorders, and hormone replacement therapy for women of reproductive age.

GNH India supplies Nomegestrol Stragen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers, including regulatory documentation and pharmacovigilance support throughout.

Manufacturer / TM Owner

Stragen Nordic A/S

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nomegestrol Stragen, a synthetic progestogen, is used in hormonal pathways related to contraception and estrogen deficiency.

  • Contraception: Provides effective oral hormonal birth control by suppressing ovulation and inducing endometrial changes.
  • Menstrual disorder management: Alleviates irregular bleeding and dysmenorrhea by stabilizing the endometrial lining.
  • Hormone replacement therapy: Replaces deficient progesterone in post‑menopausal women to maintain hormonal balance.

How It Works

  • Nomegestrol acetate acts as a selective progesterone receptor agonist. By binding to progesterone receptors in the hypothalamic‑pituitary‑ovarian axis, it inhibits the luteinizing hormone surge, thereby suppressing ovulation. It also induces secretory transformation of the endometrium, creating a hostile environment for implantation. The combined effect provides contraceptive efficacy and supports hormonal balance in replacement therapy.

Side Effects

Nomegestrol Stragen may be associated with a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset.
  • Headache: transient cranial pain.
  • Breast tenderness: mild discomfort.
  • Vaginal spotting: light bleeding between periods.

Serious or Rare Side Effects

  • Thromboembolic events: deep vein thrombosis or pulmonary embolism.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Liver dysfunction: elevated enzymes or jaundice.

Precautions & Warnings

When prescribing Nomegestrol Stragen, clinicians should consider several precautionary measures to ensure safe use.

  • Assess thrombotic risk: evaluate history of clotting disorders before initiating therapy.
  • Monitor liver function: perform baseline and periodic liver enzyme tests.
  • Screen for hormone‑sensitive cancers: avoid use in patients with active breast or endometrial cancer.
  • Counsel on smoking: advise cessation, especially in women over 35, due to increased cardiovascular risk.
  • Review concomitant medications: consider potential interactions that may affect efficacy or safety.
  • Store at ambient temperature: keep tablets below 25 °C in the original packaging, protected from moisture and light.

Avoid Interactions

Nomegestrol acetate can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers: such as rifampicin or phenytoin, which may reduce plasma levels.
  • Anticoagulants: increased risk of thrombosis when combined with estrogen‑containing products.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors: like ketoconazole, may raise drug concentrations.
  • Antiepileptic drugs: may affect hormonal balance.
  • Herbal supplements: St. John’s wort may decrease efficacy.

Frequently Asked Questions

Nomegestrol Stragen is prescribed for three primary purposes: oral hormonal contraception to prevent pregnancy, management of menstrual disorders such as irregular bleeding or dysmenorrhea, and hormone replacement therapy in post‑menopausal women to provide progesterone support.

Nomegestrol acetate is a progesterone receptor agonist. It binds to progesterone receptors in the hypothalamic‑pituitary‑ovarian axis, suppressing the luteinizing hormone surge and thereby preventing ovulation. It also induces secretory changes in the endometrium, creating conditions unsuitable for implantation.

The exact dose of Nomegestrol Stragen is determined by the prescribing clinician based on the indication, patient characteristics, and local guidelines. Healthcare professionals select the appropriate regimen and adjust it as needed; patients should follow the prescriber’s instructions precisely.

Nomegestrol Stragen is not intended for use during pregnancy because it is a hormonal contraceptive. If pregnancy occurs, the medication should be discontinued. Safety during breastfeeding has not been fully established, and clinicians usually advise caution or avoidance while nursing.

To order Nomegestrol Stragen, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with combined estrogen‑progestin pills, Nomegestrol Stragen contains only a progestogen, which may reduce estrogen‑related side effects such as breast tenderness or nausea. It offers a once‑daily oral regimen and is suitable for women who cannot take estrogen, though efficacy and safety profiles are similar to other progestogen‑only options.

Store Nomegestrol Stragen tablets at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct light, and ensure the packaging remains tightly closed until use.

Nomegestrol Stragen is taken orally, usually with a glass of water. The tablet is swallowed whole and should be taken at the same time each day to maintain consistent hormone levels. Patients should follow the dosing schedule prescribed by their healthcare provider.

The most serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe allergic reactions (anaphylaxis), and liver dysfunction indicated by elevated enzymes or jaundice. Patients should seek immediate medical attention if they experience symptoms suggestive of these conditions.

Contraindications include women with a history of thromboembolic disorders, active breast or endometrial cancer, severe liver disease, known hypersensitivity to nomegestrol acetate, or those who are pregnant. Clinicians should assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.