Product image of Non-Drowsy Decongestant (Phenylephrine Hydrochloride, Paracetamol, Caffeine) supplied by GNH India

Non-Drowsy Decongestant

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol, Caffeine
Origin:
EU

Non-Drowsy Decongestant (Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Phenylephrine Hydrochloride, Paracetamol and Caffeine, the active ingredients in Non-Drowsy Decongestant, are a combination analgesic/antipyretic and nasal decongestant presented as a tablet for oral use. It relieves nasal congestion, headache, fever and minor pain in adults.
GNH India supplies Non-Drowsy Decongestant as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wrafton Laboratories Limited

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Indications & Clinical Uses

Non‑Drowsy Decongestant, a combination analgesic/antipyretic and nasal decongestant, is used to manage common cold and flu symptom clusters.

  • Nasal congestion: reduces swelling of nasal mucosa to improve airflow.
  • Headache: alleviates pain associated with sinus pressure and tension.
  • Fever: lowers elevated body temperature.
  • Minor pain: eases aches such as sore throat or muscle discomfort.

How It Works

  • Phenylephrine Hydrochloride acts as an α1‑adrenergic agonist causing vasoconstriction of nasal mucosal vessels, which decreases swelling and improves breathing. Paracetamol reduces pain and fever by centrally inhibiting COX enzymes and modulating the endocannabinoid system. Caffeine antagonises adenosine receptors, providing central nervous system stimulation that enhances the analgesic effect of paracetamol and counteracts drowsiness.

Side Effects

Common side effects are generally mild and transient.

Common Side Effects

  • Nausea: mild stomach upset.
  • Dizziness: sensation of light‑headedness.
  • Insomnia: difficulty falling asleep.
  • Dry mouth: reduced salivation.
  • Palpitations: awareness of heartbeat.

Serious or Rare Side Effects

  • Hypertension: significant increase in blood pressure.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Liver enzyme elevation: abnormal liver function tests.
  • Seizures: rare neurologic events.

Precautions & Warnings

Before using Non‑Drowsy Decongestant, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: use with caution and under medical advice.
  • Hypertension: avoid if you have uncontrolled high blood pressure.
  • MAO inhibitors: do not combine with monoamine oxidase inhibitors.
  • Alcohol: limit intake as it may increase liver load.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture.

Avoid Interactions

Non‑Drowsy Decongestant may interact with other medicines; review the categories below.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis.
  • Other sympathomimetic decongestants: may cause excessive vasoconstriction.
  • Certain antihypertensive drugs: can reduce their effectiveness.

Moderate Interactions (Monitor Closely)

  • Anticoagulants (e.g., warfarin): paracetamol may enhance anticoagulant effect.
  • Caffeine‑containing products: may increase stimulant side effects.
  • Other analgesics (e.g., NSAIDs): monitor for additive liver or gastrointestinal risk.

Frequently Asked Questions

Non‑Drowsy Decongestant is an over‑the‑counter oral product that combines phenylephrine, paracetamol and caffeine to relieve nasal congestion, headache, fever and minor aches associated with common cold or flu in adults.

Phenylephrine narrows blood vessels in the nasal passages, reducing swelling. Paracetamol lowers pain and fever by inhibiting central COX enzymes. Caffeine blocks adenosine receptors, providing mild stimulation and enhancing the analgesic effect of paracetamol while reducing drowsiness.

The appropriate dose is determined by a prescriber or according to the product label. Patients should follow the specific instructions provided by their healthcare professional or the packaging information.

Pregnant or breastfeeding individuals should consult their healthcare provider before using this product. The safety profile has not been fully established, and professional guidance is recommended to weigh potential benefits and risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient decongestants, this combination adds paracetamol for pain and fever relief and caffeine to counteract drowsiness, offering broader symptom coverage in one tablet. It may be preferred when patients need both decongestion and analgesia without taking multiple products.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep out of reach of children.

The product is taken orally, usually with a glass of water. It should be swallowed whole and not chewed or crushed unless the label specifically permits.

Serious risks include significant hypertension, cardiac arrhythmias, severe allergic reactions such as anaphylaxis, liver enzyme elevations, and, rarely, seizures. Patients experiencing these symptoms should seek immediate medical attention.

Individuals with uncontrolled high blood pressure, known hypersensitivity to any of the ingredients, those taking monoamine oxidase inhibitors, or patients with certain cardiac conditions should avoid this medication unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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