Product image of Non-Drowsy Decongestant With Paracetamol (Phenylephrine Hydrochloride, Paracetamol, Caffeine) supplied by GNH India

Non-Drowsy Decongestant With Paracetamol

Active Ingredient:
Phenylephrine Hydrochloride, Paracetamol, Caffeine
Origin:
EU

Non-Drowsy Decongestant With Paracetamol (Phenylephrine Hydrochloride, Paracetamol, Caffeine)

Phenylephrine Hydrochloride, the active ingredient in Non‑Drowsy Decongestant With Paracetamol, is a combination (decongestant, analgesic, stimulant) presented as an oral tablet for oral use. It relieves nasal congestion, reduces fever, and eases pain associated with common cold and flu in adults and children over twelve years of age when taken as directed and provides rapid symptom relief without causing drowsiness.

GNH India supplies Non‑Drowsy Decongestant With Paracetamol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wrafton Laboratories Limited

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Indications & Clinical Uses

Non‑Drowsy Decongestant With Paracetamol is used to alleviate symptoms of the common cold and flu, targeting nasal congestion and associated discomfort.

  • Nasal congestion: reduces swelling of nasal mucosa, improving airflow.
  • Headache: alleviates pain through paracetamol’s analgesic action.
  • Fever: lowers elevated body temperature via antipyretic effect.
  • Cold‑or‑flu related pain: eases sore throat, muscle aches and general discomfort.

How It Works

  • Phenylephrine Hydrochloride acts as an α1‑adrenergic receptor agonist, causing vasoconstriction of the nasal mucosal vessels and thereby decreasing swelling and congestion. Paracetamol inhibits central cyclo‑oxygenase enzymes, reducing prostaglandin synthesis which provides analgesic and antipyretic effects. Caffeine blocks adenosine receptors, producing mild central nervous system stimulation and enhancing the analgesic potency of paracetamol, and contributes to a quicker onset of relief.

Side Effects

The combination may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Headache
  • Dizziness
  • Insomnia
  • Dry mouth

Serious or Rare Side Effects

  • Severe hypertension
  • Allergic reactions such as rash, itching or angioedema
  • Cardiac arrhythmia
  • Liver injury (rare)

Precautions & Warnings

When considering Non‑Drowsy Decongestant With Paracetamol, several safety measures should be observed.

  • Assess blood pressure: avoid use in patients with uncontrolled hypertension.
  • Cardiovascular disease: use with caution in those with heart disease or arrhythmias.
  • Pregnancy and lactation: limit use and consult a healthcare professional before taking.
  • Paracetamol limit: do not exceed the total daily paracetamol dose from all sources.
  • Concomitant sympathomimetics: avoid combining with other decongestants or MAO inhibitors.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Non‑Drowsy Decongestant With Paracetamol can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • MAO inhibitors: concurrent use may cause hypertensive crisis.
  • Other phenylephrine‑containing products: risk of excessive vasoconstriction and elevated blood pressure.
  • Additional paracetamol‑containing medications: risk of hepatotoxicity from overdose.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: phenylephrine may reduce their effectiveness, requiring blood pressure monitoring.
  • SSRIs or SNRIs: combined use can increase risk of serotonin syndrome.
  • Caffeine‑rich beverages or medications: may enhance stimulant effects and cause insomnia or jitteriness.

Frequently Asked Questions

It is an over‑the‑counter combination product intended to relieve nasal congestion, reduce fever, and ease headache, sore throat, muscle aches and other pain associated with the common cold or influenza.

Phenylephrine is an α1‑adrenergic agonist that narrows the blood vessels in the nasal lining, decreasing swelling and allowing the airways to open, which eases the feeling of a blocked nose.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight and clinical condition. Patients should follow the prescriber’s instructions and never exceed the recommended amount.

Safety has not been fully established. Women who are pregnant, planning pregnancy, or breastfeeding should consult their doctor before using the product, as the benefits must be weighed against potential risks.

Enquiries are submitted via the product page at gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike single‑ingredient decongestants, this formulation combines phenylephrine with paracetamol and caffeine, offering simultaneous relief of congestion, pain and fatigue. It provides a non‑sedating alternative to products that contain antihistamines or codeine, but it shares similar cautions regarding cardiovascular effects.

Store at room temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, heat and direct sunlight, and keep out of reach of children.

The medication is taken orally, usually with a glass of water. It may be taken with or without food, depending on the prescriber’s advice, and should be swallowed whole, not chewed or crushed.

Serious adverse events include severe hypertension, allergic reactions such as rash or swelling of the face and throat, cardiac arrhythmias, and rare liver injury from excessive paracetamol exposure. Seek immediate medical attention if any of these occur.

People with uncontrolled high blood pressure, known hypersensitivity to phenylephrine, paracetamol or caffeine, severe heart disease, or those taking monoamine oxidase inhibitors should avoid this product unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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