Product image of Noradrenalin Aguettant (Noradrenaline Tartrate) supplied by GNH India

Noradrenalin Aguettant

Active Ingredient:
Noradrenaline Tartrate
Origin:
EU

Noradrenalin Aguettant (Noradrenaline Tartrate)

Noradrenaline tartrate, the active ingredient in Noradrenalin Aguettant, is a sympathomimetic presented as a sterile intravenous solution approved in the European Union. It acts as a potent vasopressor to rapidly increase systemic vascular resistance and raise arterial pressure in patients with acute hypotension, septic shock, or cardiac arrest.

GNH India supplies Noradrenalin Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, intensive care units and emergency departments worldwide, ensuring consistent quality, regulatory compliance, and reliable cold‑chain logistics where required.

Manufacturer / TM Owner

Laboratoire Aguettant

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Noradrenalin Aguettant is a vasopressor used in critical care to manage severe circulatory failure.

  • Hypotension: restores arterial pressure by inducing vasoconstriction in patients with acute low blood pressure.
  • Septic shock: supports hemodynamics by increasing systemic vascular resistance in sepsis‑related circulatory collapse.
  • Cardiac arrest: provides immediate pressor support during resuscitation to improve coronary and cerebral perfusion.

How It Works

  • Noradrenaline tartrate acts as a direct agonist at α1‑adrenergic receptors on vascular smooth muscle. Stimulation of these receptors triggers phospholipase C activation, leading to increased intracellular calcium and potent vasoconstriction. The resulting rise in systemic vascular resistance significantly elevates mean arterial pressure, supporting organ perfusion in states of circulatory shock. Minimal β‑adrenergic activity may modestly increase heart rate and contractility.

Side Effects

Noradrenalin Aguettant may be associated with several adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache: mild to moderate headache occurring during infusion.
  • Tachycardia: increased heart rate due to β‑adrenergic stimulation.
  • Peripheral ischemia: reduced blood flow causing cold extremities.
  • Nausea: transient nausea reported in some patients.
  • Hypertension: excessive rise in blood pressure if dose is high.

Serious or Rare Side Effects

  • Cardiac arrhythmias: potentially life‑threatening rhythm disturbances.
  • Myocardial ischemia: reduced coronary perfusion leading to chest pain or infarction.
  • Tissue necrosis: severe local vasoconstriction causing skin or limb damage.
  • Pulmonary edema: fluid accumulation in lungs due to high afterload.
  • Severe hypertension: dangerous spikes in arterial pressure requiring immediate intervention.

Precautions & Warnings

When using Noradrenalin Aguettant, clinicians should observe specific precautions to minimize risks.

  • Dose titration: adjust infusion rate to achieve target blood pressure while monitoring hemodynamics.
  • Cardiac monitoring: continuous ECG and heart rate observation for arrhythmias.
  • Peripheral perfusion: assess limb circulation regularly to detect ischemia.
  • Fluid balance: ensure adequate intravascular volume before initiating therapy.
  • Contraindications: avoid use in patients with known hypersensitivity to noradrenaline or catecholamines.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Noradrenalin Aguettant can interact with other agents, altering its pressor effect or safety profile.

Major Interactions (Avoid)

  • β‑blockers: may blunt the β‑adrenergic component, reducing heart rate response.
  • MAO inhibitors: increase risk of hypertensive crisis when combined.
  • Vasodilators: concurrent use can counteract pressor effect, requiring higher doses.

Moderate Interactions (Monitor Closely)

  • Calcium channel blockers: may enhance vasoconstriction and raise blood pressure.
  • Tricyclic antidepressants: additive sympathomimetic activity may cause excessive hypertension.
  • Diuretics: can exacerbate hypovolemia, intensifying vasopressor requirements.

Frequently Asked Questions

Noradrenalin Aguettant is a prescription‑only vasopressor indicated for the rapid restoration of blood pressure in patients with acute hypotension, septic shock, or cardiac arrest. It is administered in intensive care and emergency settings to support circulatory function until the underlying cause can be treated.

Noradrenaline tartrate acts as a direct agonist at alpha‑1 adrenergic receptors on vascular smooth muscle. Activation of these receptors increases intracellular calcium, causing potent vasoconstriction, which raises systemic vascular resistance and elevates arterial pressure. Limited beta‑adrenergic activity may also modestly increase heart rate and contractility.

The dosing regimen for Noradrenalin Aguettant is individualized and set by the treating physician based on the patient’s hemodynamic status, target blood pressure, and response to therapy. Clinicians typically start with a low infusion rate and titrate upward while continuously monitoring vital signs.

Safety data for noradrenaline tartrate in pregnancy and lactation are limited. The drug should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and it is generally reserved for life‑threatening situations where alternative therapies are unsuitable.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Noradrenalin Aguettant is the first‑line vasopressor for most shock states because of its strong alpha‑adrenergic activity and relatively predictable effect on blood pressure. Compared with dopamine, it has less tachyarrhythmic potential, and unlike epinephrine, it produces less increase in heart rate, making it preferable when tachycardia is a concern.

The product should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. It should be kept in its original packaging until use to maintain stability and potency.

Noradrenalin Aguettant is supplied as a sterile solution for intravenous infusion. It is typically administered through a central or large peripheral vein using a calibrated infusion pump, with the rate adjusted to achieve the desired blood pressure target while monitoring cardiovascular parameters.

Serious adverse events include severe hypertension, cardiac arrhythmias, myocardial ischemia, tissue necrosis from extreme peripheral vasoconstriction, and pulmonary edema. Prompt recognition and immediate intervention are essential if any of these complications arise during therapy.

Noradrenalin Aguettant is contraindicated in patients with known hypersensitivity to noradrenaline or other catecholamines. Caution is also advised in individuals with severe peripheral vascular disease, uncontrolled arrhythmias, or those receiving MAO inhibitors, as the risk of hypertensive crises may be heightened.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Noradrenaline Tartrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT