Product image of Noradrenalina Tartrato Galenica Senese (Noradrenaline Tartrate) supplied by GNH India

Noradrenalina Tartrato Galenica Senese

Active Ingredient:
Noradrenaline Tartrate
Origin:
EU

Noradrenalina Tartrato Galenica Senese (Noradrenaline Tartrate)

Noradrenaline Tartrate, the active ingredient in Noradrenalina Tartrato Galenica Senese, is a sympathomimetic presented as an injectable solution for intravenous use. It is employed to raise blood pressure in patients experiencing acute hypotension, septic shock, cardiogenic shock, or post‑operative hypotension.

GNH India supplies Noradrenalina Tartrato Galenica Senese as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company follows EU GMP standards and offers regulated distribution to healthcare institutions across multiple continents. Our logistics network ensures timely delivery and appropriate cold‑chain handling for injectable products.

Manufacturer / TM Owner

Industria Farmaceutica Galenica Senese S.R.L..

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Indications & Clinical Uses

  • Noradrenaline Tartrate is used as a vasopressor to counteract severe hypotension in critical care settings.
  • Acute hypotension: rapidly restores arterial pressure to maintain organ perfusion.
  • Septic shock: improves systemic vascular resistance and tissue perfusion.
  • Cardiogenic shock: supports cardiac output while increasing blood pressure.
  • Post‑operative hypotension: stabilises haemodynamics after surgery.

How It Works

  • Noradrenaline Tartrate acts as a direct agonist at alpha‑1 and beta‑1 adrenergic receptors. Stimulation of alpha‑1 receptors produces peripheral vasoconstriction, raising systemic vascular resistance, while beta‑1 activation increases myocardial contractility and heart rate, together elevating cardiac output and arterial pressure.

Side Effects

Noradrenaline Tartrate may cause a range of adverse reactions, varying from mild to life‑threatening.

Common Side Effects

  • Tachycardia
  • Headache
  • Anxiety
  • Peripheral ischemia
  • Nausea

Serious or Rare Side Effects

  • Life‑threatening arrhythmias
  • Myocardial ischemia or infarction
  • Severe hypertension
  • Tissue necrosis at the infusion site
  • Pulmonary edema
  • Cardiac arrest

Precautions & Warnings

  • Noradrenaline Tartrate requires careful monitoring and specific safety measures.
  • Cardiovascular monitoring: continuous blood pressure and heart‑rate observation is essential.
  • Dosage titration: infusion rate should be adjusted based on real‑time haemodynamic response.
  • Electrolyte balance: monitor serum potassium and calcium levels during therapy.
  • Drug interactions: avoid concurrent use with monoamine‑oxidase inhibitors.
  • Pregnancy and lactation: use only if potential benefits outweigh risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Noradrenaline Tartrate can interact with several drug classes, influencing its safety profile.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis.
  • Tricyclic antidepressants: additive vasoconstriction.
  • Beta‑blockers: may blunt intended cardiac response.
  • Calcium channel blockers: increased arrhythmia risk.

Moderate Interactions (Monitor Closely)

  • Diuretics: potential electrolyte disturbances.
  • Inhaled anesthetics: may potentiate hypotensive effects.

Frequently Asked Questions

Noradrenalina Tartrato Galenica Senese contains noradrenaline tartrate, a vasopressor used in intensive‑care settings to raise blood pressure in patients with acute hypotension, septic shock, cardiogenic shock, or post‑operative hypotension.

The drug directly stimulates alpha‑1 receptors, causing peripheral vasoconstriction, and beta‑1 receptors, increasing heart‑rate and contractility. This dual action raises systemic vascular resistance and cardiac output, thereby improving arterial pressure.

The dose of noradrenaline tartrate is individualized. A qualified prescriber determines the infusion rate based on the patient’s haemodynamic status, response to therapy, and clinical guidelines.

Safety data are limited. Noradrenaline tartrate should only be used in pregnancy or while breastfeeding if the potential therapeutic benefit justifies the potential risk to the fetus or infant.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Noradrenaline tartrate is a first‑line sympathomimetic with potent alpha‑1 and beta‑1 activity, offering rapid blood‑pressure support. Compared with agents such as dopamine or phenylephrine, it provides a balanced increase in vascular tone and cardiac output, making it preferred for many shock states.

The injectable solution must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Use aseptic technique during preparation and administer promptly after removal from refrigeration.

Noradrenaline tartrate is given intravenously, typically as a continuous infusion. The solution is diluted according to institutional protocol and administered via a calibrated infusion pump to allow precise titration.

Serious risks include life‑threatening arrhythmias, severe hypertension, myocardial ischemia, tissue necrosis at the infusion site, pulmonary edema, and cardiac arrest. Continuous cardiac and haemodynamic monitoring is essential to detect these events early.

Patients with known hypersensitivity to noradrenaline or any formulation component, those receiving monoamine‑oxidase inhibitors, or individuals with uncontrolled severe hypertension should not be given this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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