Product image of Noradrenaline (Tartrate) Renaudin (Noradrenaline Tartrate) supplied by GNH India

Noradrenaline (Tartrate) Renaudin

Active Ingredient:
Noradrenaline Tartrate
Origin:
EU

Noradrenaline (Tartrate) Renaudin (Noradrenaline Tartrate)

Noradrenaline, the active ingredient in Noradrenaline (Tartrate) Renaudin, is a vasopressor presented as an injection for intravenous use. It is employed to raise blood pressure in acute hypotensive states such as septic shock, cardiac arrest, and other critical care situations where rapid circulatory support is required.

GNH India supplies Noradrenaline (Tartrate) Renaudin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company follows global quality standards and provides cold‑chain logistics for this injectable product.

Manufacturer / TM Owner

Laboratoire Renaudin

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Noradrenaline is used as a potent vasopressor in critical care settings to manage severe hypotension and circulatory failure.

  • Hypotension: restores vascular tone and raises systemic blood pressure in acute low‑pressure states.
  • Cardiac arrest: provides immediate vasoconstriction to support coronary perfusion during resuscitation efforts.
  • Septic shock: counteracts vasodilatory shock by increasing peripheral vascular resistance and improving organ perfusion.

How It Works

  • Noradrenaline acts as an agonist at alpha‑adrenergic receptors, primarily α1, causing smooth‑muscle contraction in peripheral vessels and resulting in vasoconstriction and increased systemic vascular resistance. It also stimulates β1 receptors modestly, enhancing heart rate and myocardial contractility, which together raise arterial pressure and improve organ perfusion during shock states.

Side Effects

Noradrenaline may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Hypertension: excessive rise in blood pressure.
  • Tachycardia: increased heart rate.
  • Arrhythmias: irregular cardiac rhythm.
  • Headache: pressure‑type head discomfort.

Serious or Rare Side Effects

  • Myocardial ischemia: reduced heart muscle blood flow.
  • Severe hypertension: dangerously high arterial pressure.
  • Tissue necrosis at extravasation site: local tissue death if the drug leaks from the vein.
  • Cardiac arrest: loss of heart function.
  • Pulmonary edema: fluid accumulation in lungs.

Precautions & Warnings

When using Noradrenaline, clinicians should observe several safety measures to minimize risks.

  • Cardiac monitoring: continuous ECG and arterial pressure tracking.
  • Dose titration: adjust infusion to achieve target mean arterial pressure.
  • Contraindications: avoid in patients with pheochromocytoma or uncorrected hypovolemia.
  • Caution in coronary artery disease: monitor for myocardial ischemia.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Noradrenaline can interact with other medications, influencing cardiovascular responses.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis.
  • Tricyclic antidepressants: additive pressor effect.
  • Beta‑blockers: may blunt expected tachycardia.

Moderate Interactions (Monitor Closely)

  • Vasodilators (e.g., nitroglycerin, ACE inhibitors): may require higher Noradrenaline doses.
  • Calcium channel blockers: additive cardiovascular effects.
  • Diuretics: volume depletion can enhance hypotensive response.

Frequently Asked Questions

Noradrenaline (Tartrate) Renaudin is employed as an intravenous vasopressor to treat severe hypotension, cardiac arrest, and septic shock. It provides rapid vasoconstriction and supports blood pressure in critical care environments where immediate circulatory support is essential.

Noradrenaline activates alpha‑1 adrenergic receptors on vascular smooth muscle, causing vasoconstriction and raising systemic vascular resistance. It also stimulates beta‑1 receptors in the heart, modestly increasing heart rate and contractility, together elevating arterial pressure and improving organ perfusion.

The dosing regimen for Noradrenaline is individualized. A prescriber determines the infusion rate based on the patient’s hemodynamic status, target mean arterial pressure, and response to therapy. Doses are titrated carefully under continuous monitoring.

Safety data for Noradrenaline in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where needed) and import documentation.

Noradrenaline primarily stimulates alpha‑1 receptors, producing strong vasoconstriction with modest beta‑1 activity, making it the preferred first‑line agent for most shock states. Dopamine has dose‑dependent effects on dopaminergic, beta‑1, and alpha receptors, which can lead to more variable heart rate responses and arrhythmias.

Noradrenaline (Tartrate) Renaudin should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use to maintain stability.

The drug is supplied as a sterile solution for intravenous injection. It is typically administered via a controlled infusion pump, allowing precise titration of the dose while continuous hemodynamic monitoring is performed.

Serious risks include severe hypertension, myocardial ischemia, tissue necrosis from extravasation, cardiac arrhythmias, and, in rare cases, cardiac arrest. Prompt recognition and management of these events are essential during therapy.

Noradrenaline is contraindicated in patients with known pheochromocytoma, uncorrected hypovolemia, or severe peripheral vascular disease where vasoconstriction could worsen tissue perfusion. Clinicians should assess each patient’s condition before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Noradrenaline Tartrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT