Product image of Norethisterone Wockhardt Uk (Norethisterone) supplied by GNH India

Norethisterone Wockhardt Uk

Active Ingredient:
Norethisterone
Origin:
EU

Norethisterone Wockhardt Uk (Norethisterone)

Norethisterone, the active ingredient in Norethisterone Wockhardt Uk, is a progestogen presented as a tablet for oral use. It is used to manage menstrual disorders, endometriosis, and as a hormonal contraceptive in women of reproductive age.

GNH India supplies Norethisterone Wockhardt Uk as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wockhardt Uk Ltd

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Indications & Clinical Uses

  • Norethisterone acts on the hormonal pathways that regulate the menstrual cycle and ovulation.
  • Menstrual disorders: regulates irregular bleeding and reduces dysmenorrhea.
  • Endometriosis: suppresses ectopic endometrial tissue growth and alleviates pelvic pain.
  • Contraception: prevents ovulation and creates an unfavorable endometrial environment for implantation.
  • Secondary amenorrhea: induces withdrawal bleeding and restores menstrual cycles.

How It Works

  • Norethisterone is a synthetic progestogen that binds to progesterone receptors in the hypothalamus and ovary, suppressing the luteinizing hormone surge, inhibiting ovulation, and inducing endometrial changes that prevent implantation and stabilize the menstrual lining.

Side Effects

Norethisterone may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Weight gain
  • Mood changes
  • Irregular bleeding

Serious or Rare Side Effects

  • Venous thromboembolism
  • Severe allergic reaction (anaphylaxis)
  • Hepatic dysfunction
  • Depression or mood disorders
  • Visual disturbances
  • Severe abdominal pain

Precautions & Warnings

  • Before prescribing Norethisterone, clinicians should evaluate individual risk factors and contraindications.
  • Pregnancy: contraindicated; avoid use during pregnancy.
  • Breastfeeding: not recommended; assess risk versus benefit.
  • History of thromboembolism: avoid due to increased clot risk.
  • Liver disease: use with caution; monitor hepatic function.
  • Smoking over 15 cigarettes/day: contraindicated in women over 35.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Norethisterone can interact with several drug classes, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Combined hormonal contraceptives containing estrogen: increased risk of thromboembolism.
  • Antifungal azoles (e.g., ketoconazole): may increase plasma levels of norethisterone.
  • Antiretroviral protease inhibitors: may reduce contraceptive effectiveness.

Moderate Interactions (Monitor Closely)

  • Rifampicin and other enzyme inducers: may lower plasma concentration.
  • Anticonvulsants (phenytoin, carbamazepine): may reduce efficacy.
  • St. John's Wort: may decrease drug levels and effectiveness.

Frequently Asked Questions

Norethisterone Wockhardt Uk is prescribed to treat menstrual disorders such as irregular bleeding and dysmenorrhea, to manage endometriosis‑related pelvic pain, to provide hormonal contraception, and to induce withdrawal bleeding in cases of secondary amenorrhea.

Norethisterone is a synthetic progestogen that binds to progesterone receptors, suppresses the luteinizing hormone surge, prevents ovulation, and induces endometrial changes that make the uterine lining less suitable for implantation.

The dosage of Norethisterone Wockhardt Uk is determined by the prescribing clinician based on the specific indication, patient characteristics, and treatment goals. Patients should follow the dose and schedule provided by their healthcare professional.

Norethisterone is contraindicated during pregnancy because it can affect fetal development. It is not recommended for breastfeeding mothers; if use is considered, the benefits must outweigh potential risks to the infant.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Norethisterone is a progestogen‑only option, whereas many combined oral contraceptives contain both estrogen and progestogen. Progestogen‑only regimens avoid estrogen‑related risks such as increased blood pressure and certain clotting concerns, but may have different bleeding patterns and require strict timing of doses.

Store Norethisterone tablets at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Norethisterone is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious risks include venous thromboembolism, severe allergic reactions such as anaphylaxis, hepatic dysfunction, and significant mood changes or depression. Patients should seek immediate medical attention if they experience symptoms like unexplained swelling, severe abdominal pain, or signs of an allergic reaction.

Norethisterone should not be used by women who are pregnant, are breastfeeding, have a history of thromboembolic disorders, have active liver disease, or who smoke more than 15 cigarettes per day and are over 35 years of age. Contraindications also include known hypersensitivity to the drug.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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