Product image of Norit 200 (Charcoal, Activated) supplied by GNH India

Norit 200

Active Ingredient:
Charcoal, Activated
Origin:
EU

Norit 200 (Charcoal, Activated)

Activated charcoal, the active ingredient in Norit 200, is an adsorbent presented as a powdered oral preparation for oral use. It is employed to bind toxins and gases in the gastrointestinal tract, limiting systemic absorption in cases of acute poisoning or drug overdose.
GNH India supplies Norit 200 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Norit Nederland B.V.

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Indications & Clinical Uses

Norit 200 is an activated charcoal product used for gastrointestinal decontamination and toxin adsorption.

  • Acute poisoning: reduces absorption of ingested toxins and lowers systemic exposure.
  • Drug overdose: binds a broad range of oral medications to limit their bioavailability.
  • Gastrointestinal decontamination: adsorbs gases and substances in the gut to alleviate symptoms and prevent further complications.

How It Works

  • Activated charcoal consists of a highly porous carbon matrix with a large surface area that physically adsorbs molecules through van der Waals forces. When administered orally, it binds toxins, drugs, and gases present in the gastrointestinal lumen, forming complexes that are not absorbed and are eliminated in the feces, thereby decreasing systemic exposure.

Side Effects

Activated charcoal is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Constipation: reduced bowel motility leading to hard stools.
  • Black or tarry stools: discoloration due to charcoal passage.
  • Nausea: mild stomach discomfort after ingestion.
  • Vomiting: occasional expulsion of the preparation.
  • Abdominal discomfort: cramping or bloating.

Serious or Rare Side Effects

  • Aspiration pneumonia: inhalation of charcoal particles into the lungs.
  • Bowel obstruction: blockage from accumulated charcoal mass.
  • Electrolyte imbalance: rare shifts due to prolonged use.
  • Allergic reaction: rash, itching, or swelling in sensitive individuals.

Precautions & Warnings

Before using Norit 200, consider the following safety measures.

  • Timing of ingestion: administer as soon as possible after toxin exposure.
  • Airway protection: ensure a protected airway in patients with reduced consciousness.
  • Contraindicated substances: avoid use when ingested material includes iron, lithium, or cyanide salts.
  • Hydration status: monitor for dehydration, especially in children.
  • Monitoring: observe for signs of bowel obstruction or respiratory compromise.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Activated charcoal can affect the absorption of many concomitant medications.

Major Interactions (Avoid)

  • Oral anticoagulants (e.g., warfarin): may reduce therapeutic effect.
  • Digoxin: adsorption can lower plasma concentrations.
  • Antidepressants (tricyclics, SSRIs): decreased absorption.
  • Antiepileptic drugs (phenytoin, carbamazepine): reduced efficacy.
  • Certain antibiotics (tetracyclines, quinolones): diminished bioavailability.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: possible reduction in hormone levels.
  • Antacids: may alter charcoal binding capacity.
  • Statins: potential decrease in absorption.
  • Vitamin supplements: reduced uptake of fat‑soluble vitamins.

Frequently Asked Questions

Norit 200 is an oral activated charcoal product used primarily for gastrointestinal decontamination. It helps bind and eliminate ingested toxins, drugs, and gases in cases of acute poisoning, drug overdose, or when rapid removal of harmful substances from the gut is required.

Activated charcoal works by providing a highly porous carbon surface that adsorbs molecules through physical forces. When taken orally, it captures toxins, medications, and gases in the gastrointestinal tract, forming complexes that are not absorbed and are expelled in the stool, thereby limiting systemic exposure.

The dose of Norit 200 is individualized and set by a qualified healthcare professional based on factors such as the type and amount of toxin ingested, the time elapsed since exposure, patient age, weight, and clinical condition. No fixed dosing regimen is provided in the product information.

Safety data for activated charcoal in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Use should only be considered when the potential benefit outweighs any possible risk, and it must be prescribed by a clinician familiar with the patient’s condition.

To order Norit 200, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any special handling), and necessary import documentation.

Norit 200, like other activated charcoal preparations, offers broad‑spectrum adsorption of many toxins and drugs, making it a versatile first‑line option. Compared with specific antidotes, it does not neutralize the toxin chemically but reduces absorption. Its safety profile is well established, though it lacks activity against metals such as iron or lithium, which require alternative agents.

Store Norit 200 at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, heat, and direct sunlight to maintain product integrity and prevent clumping of the powdered form.

Norit 200 is administered orally. The powdered form is typically mixed with a small amount of water or another suitable liquid to form a slurry, which the patient drinks promptly. Administration should be performed under medical supervision, especially in emergency settings, to ensure correct technique and dosing.

The most serious risks include aspiration of the charcoal into the lungs, which can cause pneumonia, and bowel obstruction from accumulated charcoal mass. Rarely, severe allergic reactions or significant electrolyte disturbances may occur. Prompt medical evaluation is essential if any of these complications are suspected.

Norit 200 should be avoided in patients with a compromised airway who are not protected by intubation, in individuals who have ingested substances such as iron, lithium, or cyanide salts, and in those with known hypersensitivity to activated charcoal. It is also contraindicated when there is a risk of gastrointestinal perforation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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