Product image of Norlevo (Levonorgestrel) supplied by GNH India

Norlevo

Active Ingredient:
Levonorgestrel
Origin:
EU

Norlevo (Levonorgestrel)

Levonorgestrel, the active ingredient in Norlevo, is a progestogen presented as an oral tablet for oral use. The tablet is formulated for rapid absorption and is approved for emergency contraception. It is employed to prevent pregnancy after unprotected sexual intercourse in women of reproductive age and can be taken up to 72 hours after intercourse.

GNH India supplies Norlevo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality through rigorous testing and provides global logistics support.

Manufacturer / TM Owner

Laboratoire Hra Pharma

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Indications & Clinical Uses

Norlevo (levonorgestrel) is used within the emergency contraception pathway to prevent unintended pregnancy.

  • Emergency contraception: prevents pregnancy when taken within 72 hours after unprotected intercourse.
  • Contraceptive failure backup: provides a rescue option after a missed or ineffective regular hormonal contraceptive dose.
  • Post‑coital contraception: reduces the risk of implantation when administered promptly after sexual exposure.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamic‑pituitary‑ovarian axis, inhibiting or delaying the luteinizing hormone surge and thereby preventing ovulation. It may also impair fertilization by altering tubal motility and, if ovulation has already occurred, can hinder implantation of a fertilized egg by modifying the endometrial environment.

Side Effects

Levonorgestrel may cause a range of adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects

  • Nausea
  • Headache
  • Fatigue
  • Breast tenderness

Serious or Rare Side Effects

  • Allergic reaction (rash, swelling, difficulty breathing)
  • Severe abdominal pain or persistent vomiting
  • Unusual vaginal bleeding

Precautions & Warnings

When using Norlevo, consider the following precautions to ensure safe and effective use.

  • Timing of intake: take as soon as possible after unprotected intercourse, preferably within 72 hours.
  • Contraindications: avoid if there is a known hypersensitivity to levonorgestrel or any tablet excipients.
  • Medical conditions: use with caution in women with liver disease, hormonal disorders, or uncontrolled epilepsy.
  • Pregnancy testing: not required before use, but the product will not terminate an established pregnancy.
  • Drug interactions: be aware of enzyme‑inducing medications that may reduce efficacy.
  • Store at ambient temperature: keep below 25°C, retain in the original pack, and protect from moisture.

Avoid Interactions

Levonorgestrel may interact with other medicines, affecting its effectiveness or safety.

Major Interactions (Avoid)

  • Rifampicin, phenobarbital, carbamazepine, phenytoin: potent enzyme inducers that markedly reduce levonorgestrel plasma levels.
  • St. John's wort: herbal inducer that may lower effectiveness.

Moderate Interactions (Monitor Closely)

  • Azole antifungals (e.g., ketoconazole): may increase levonorgestrel concentrations.
  • Protease inhibitor antiretrovirals: can alter metabolism, requiring clinical monitoring.
  • Combined hormonal contraceptives: additive progestogenic effect may increase side‑effect risk.

Frequently Asked Questions

Norlevo is an oral emergency contraceptive containing levonorgestrel. It is intended to prevent pregnancy after unprotected sexual intercourse or contraceptive failure when taken within 72 hours. The product provides a rapid, non‑prescription option for women seeking post‑coital birth control.

Levonorgestrel acts primarily by binding to progesterone receptors, which suppresses the luteinizing hormone surge and delays or inhibits ovulation. If ovulation has already occurred, it can alter tubal motility and the endometrial lining, reducing the chance of fertilization and implantation of a fertilized egg.

The specific dose of Norlevo is determined by the prescribing healthcare professional or the product label. In most jurisdictions the medication is supplied as a single oral tablet that should be taken as soon as possible after the relevant sexual exposure.

Norlevo is not intended for use during an established pregnancy and will not terminate an existing pregnancy. Limited data suggest that occasional use of levonorgestrel does not pose a significant risk to breastfeeding infants, but women should discuss any concerns with their healthcare provider.

To request Norlevo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will ask for trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any required import documentation.

The primary alternative is ulipristal acetate (e.g., Ella). Ulipristal can be effective up to 120 hours after intercourse, whereas levonorgestrel‑based products like Norlevo are recommended within 72 hours. Levonorgestrel is generally less expensive and available over the counter in many regions, while ulipristal often requires a prescription.

Norlevo tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Norlevo is taken as a single oral tablet. The tablet should be swallowed whole with water as soon as possible after unprotected intercourse, ideally within 72 hours. No food restrictions are required, but taking the tablet with a full glass of water may aid absorption.

Serious but rare risks include severe allergic reactions such as rash, swelling, or difficulty breathing, persistent or heavy vaginal bleeding, and intense abdominal pain or vomiting. If any of these occur, medical attention should be sought immediately.

Norlevo should be avoided by individuals with a known hypersensitivity to levonorgestrel or any tablet excipients. Women who are already pregnant, have severe liver disease, or have a history of thromboembolic disorders should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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