Product image of Norlevo (Levonorgestrel) supplied by GNH India

Norlevo

Active Ingredient:
Levonorgestrel
Origin:
EU

Norlevo (Levonorgestrel)

Levonorgestrel, the active ingredient in Norlevo, is a synthetic progestogen presented as a 1.5 mg tablet for oral administration. It is used as emergency contraception to reduce the risk of pregnancy after unprotected sexual intercourse or contraceptive failure in women of reproductive age.

GNH India supplies Norlevo as a licensed, Good Distribution Practice‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and offers reliable logistics for bulk and individual orders across multiple regions.

Manufacturer / TM Owner

Laboratoire Hra Pharma

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Indications & Clinical Uses

Norlevo (levonorgestrel) is used in the reproductive health pathway as an emergency contraceptive.

  • Unprotected intercourse: reduces the chance of pregnancy when taken within 72 hours after sex.
  • Contraceptive failure: provides backup protection after a missed or ineffective regular contraceptive dose.
  • Delayed ovulation: inhibits or postpones ovulation to prevent fertilisation.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamic‑pituitary‑gonadal axis, suppressing the luteinising hormone surge and thereby inhibiting or delaying ovulation. If ovulation has already occurred, it may impair fertilisation by altering tubal motility and cervical mucus, and can reduce the likelihood of implantation by modifying the endometrial lining. Its activity is dose‑dependent and most effective when administered as soon as possible after the contraceptive challenge.

Side Effects

Levonorgestrel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild stomach upset after taking the tablet.
  • Headache: transient mild to moderate headache.
  • Fatigue: feeling of tiredness or weakness.
  • Menstrual changes: spotting, earlier or delayed period.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Chest pain or palpitations: may indicate cardiovascular issues.
  • Persistent abdominal pain or vomiting blood: could signal gastrointestinal complications.

Precautions & Warnings

When using Norlevo, consider the following precautions.

  • Timing of intake: take as soon as possible after unprotected intercourse, ideally within 72 hours.
  • Weight considerations: effectiveness may be reduced in individuals with BMI >30 kg/m².
  • Pregnancy testing: avoid use if already pregnant.
  • Medication interactions: avoid concomitant use with enzyme‑inducing drugs that may lower efficacy.
  • Medical conditions: consult a healthcare professional if you have liver disease, uncontrolled hypertension, or a history of thromboembolic disorders.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levonorgestrel can interact with several medicines; monitor accordingly.

Major Interactions (Avoid)

  • Enzyme inducers (e.g., rifampicin, carbamazepine, phenytoin): may significantly reduce levonorgestrel effectiveness.
  • Antifungal agents (e.g., griseofulvin): may lower plasma levels.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., valproic acid): may modestly reduce efficacy.
  • Certain antibiotics (e.g., ampicillin, tetracycline): limited evidence of interaction, monitor clinical response.
  • Herbal supplements (e.g., St. John’s wort): may decrease effectiveness.

Frequently Asked Questions

Norlevo is an oral emergency contraceptive containing levonorgestrel. It is intended to reduce the risk of pregnancy after unprotected sexual intercourse or when a regular contraceptive method fails, and is used by women of reproductive age within a defined time window after the event.

Levonorgestrel works primarily by binding to progesterone receptors, suppressing the luteinising hormone surge and thereby inhibiting or delaying ovulation. If ovulation has already occurred, it may interfere with fertilisation and alter the endometrial environment, reducing the chance of implantation.

The specific dosing regimen for Norlevo is determined by the prescribing healthcare professional. In most clinical practice, a single 1.5 mg tablet is administered, but the exact instructions should be confirmed with a qualified prescriber.

Norlevo is not intended for use during an established pregnancy and should be avoided if pregnancy is already confirmed. Limited systemic exposure occurs during breastfeeding, but women should discuss any concerns with their healthcare provider before use.

To order Norlevo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative is ulipristal acetate (e.g., Ella). Both are taken as a single oral dose, but ulipristal remains effective up to 120 hours after intercourse, whereas levonorgestrel is most effective within 72 hours. Ulipristal may have a slightly higher efficacy in later time windows but requires a prescription in many regions.

Norlevo tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and keep out of reach of children.

Norlevo is taken orally as a single tablet. The tablet should be swallowed whole with water as soon as possible after the contraceptive incident, ideally within the recommended time frame for maximum effectiveness.

Serious but rare risks include severe allergic reactions such as anaphylaxis, chest pain or palpitations that may indicate cardiovascular problems, and persistent abdominal pain or vomiting blood, which could signal gastrointestinal complications or an ectopic pregnancy. Immediate medical attention is required if any of these occur.

Norlevo should not be used by women who are already pregnant, have a known hypersensitivity to levonorgestrel or any tablet excipients, or have certain medical conditions such as uncontrolled hypertension, severe liver disease, or a history of thromboembolic disorders without medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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