Product image of Norlevo (Levonorgestrel) supplied by GNH India

Norlevo

Active Ingredient:
Levonorgestrel
Origin:
EU

Norlevo (Levonorgestrel)

Levonorgestrel, the active ingredient in Norlevo, is a progestin presented as an oral tablet for oral use. It is used for emergency contraception after unprotected intercourse in women of reproductive age.

GNH India supplies Norlevo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Hra Pharma

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Indications & Clinical Uses

Levonorgestrel is a progestin used in the hormonal pathway of emergency contraception.

  • Unprotected intercourse: reduces the risk of pregnancy when taken within 72 hours after exposure.
  • Contraceptive failure: provides backup protection after a missed dose of regular hormonal contraception.
  • Emergency contraception for women of reproductive age: offers a non‑prescription option to prevent unintended pregnancy.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamic‑pituitary‑ovarian axis, inhibiting or delaying the luteinising hormone surge and ovulation. By preventing the release of a mature oocyte, it reduces the chance of fertilisation, and it may also impair implantation of a fertilised egg in the uterine lining.

Side Effects

Levonorgestrel is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Abdominal pain or cramps: transient discomfort.
  • Headache: occasional tension‑type headache.
  • Dizziness or light‑headedness.
  • Fatigue or tiredness.
  • Menstrual changes: spotting, earlier or later onset of the next period.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Chest pain or palpitations.
  • Persistent vomiting or vomiting blood.
  • Severe abdominal pain that does not resolve.
  • Signs of liver dysfunction: jaundice or dark urine.

Precautions & Warnings

When using Norlevo, consider the following safety measures.

  • Timing of intake: take as soon as possible after unprotected intercourse for maximum effectiveness.
  • Weight considerations: efficacy may be reduced in individuals with higher body weight or BMI.
  • Medical history: disclose liver disease, hormonal disorders, or previous thromboembolic events to a healthcare professional.
  • Concurrent medications: review all current medicines for potential interactions.
  • Pregnancy testing: the product is not intended for use if pregnancy is already established.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Levonorgestrel may interact with other medicines that affect hormone metabolism.

Major Interactions (Avoid)

  • Rifampicin or other strong enzyme inducers: can markedly lower contraceptive effectiveness.
  • Anticonvulsants such as carbamazepine, phenytoin, or phenobarbital: may reduce plasma levels.
  • St. John’s wort: herbal inducer that can diminish efficacy.

Moderate Interactions (Monitor Closely)

  • Hormonal contraceptives used concurrently: backup non‑hormonal contraception may be advisable.
  • Antifungal azoles (e.g., ketoconazole): may increase levonorgestrel concentrations.
  • Certain antiretroviral protease inhibitors: potential alteration of drug levels requiring clinical monitoring.

Frequently Asked Questions

Norlevo is an oral emergency contraceptive containing levonorgestrel. It is taken after unprotected sexual intercourse or contraceptive failure to reduce the chance of an unintended pregnancy. The product is intended for women of reproductive age and is most effective when used as soon as possible within 72 hours of the event.

Levonorgestrel acts by binding to progesterone receptors, which suppresses the luteinising hormone surge and delays or prevents ovulation. If ovulation has already occurred, the drug may interfere with fertilisation or implantation of a fertilised egg, thereby lowering the probability of pregnancy.

The specific dosing regimen for Norlevo is determined by a prescribing healthcare professional based on the product’s labeling and the individual’s circumstances. Patients should follow the instructions provided by their clinician or pharmacist and not alter the dose on their own.

Norlevo is intended for use before pregnancy is established; it is not a treatment for an existing pregnancy. Limited data are available on its safety during breastfeeding, but the amount transferred to breast milk is considered low. Women should discuss any concerns with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details and any required import documentation.

Norlevo contains levonorgestrel, a progestin that is widely used for emergency contraception. Compared with ulipristal acetate, another oral option, levonorgestrel is generally less effective after 72 hours but is available over‑the‑counter in many regions. Both classes share similar safety profiles, though drug‑interaction potentials differ.

Norlevo tablets should be stored at ambient temperature, below 25 °C. Keep them in the original blister pack, protect from moisture, direct sunlight and excessive heat. Do not store in bathrooms or near kitchen appliances that generate steam.

Norlevo is taken orally as a single tablet. The tablet should be swallowed whole with water, preferably as soon as possible after the qualifying event. No food restrictions are required, but taking the tablet with a full glass of water can help reduce nausea.

Serious but rare risks include severe allergic reactions such as rash, swelling, or difficulty breathing, and signs of liver dysfunction like jaundice. If any of these symptoms occur, medical attention should be sought immediately. Persistent vomiting or severe abdominal pain also warrant prompt evaluation.

Norlevo should be avoided by individuals with known hypersensitivity to levonorgestrel or any tablet excipients. Women who are already pregnant, have uncontrolled severe liver disease, or have a history of thromboembolic disorders should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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