Product image of Norlevo (Levonorgestrel) supplied by GNH India

Norlevo

Active Ingredient:
Levonorgestrel
Origin:
EU

Norlevo (Levonorgestrel)

Levonorgestrel, the active ingredient in Norlevo, is a progestin presented as a tablet for oral use. It is indicated for emergency contraception to prevent pregnancy after unprotected intercourse or contraceptive failure in women of reproductive age.

GNH India supplies Norlevo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for regulated markets and adhering to strict quality standards with global logistics support.

Manufacturer / TM Owner

Laboratoire Hra Pharma

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Indications & Clinical Uses

Levonorgestrel, a progestin used in emergency contraception, works by interfering with ovulation and fertilization.

  • Unprotected intercourse: prevents pregnancy when taken within 72 hours after exposure.
  • Contraceptive failure: provides a backup method after missed or ineffective regular contraception.
  • Emergency contraception: offers a non‑prescription option for women seeking rapid pregnancy prevention.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamic‑pituitary‑ovarian axis, inhibiting the luteinizing hormone surge and thereby preventing or delaying ovulation. It may also alter tubal motility and endometrial receptivity, reducing the likelihood of fertilization and implantation if ovulation has already occurred. The drug does not terminate an established pregnancy.

Side Effects

Levonorgestrel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild stomach upset.
  • Headache: transient cranial discomfort.
  • Fatigue: temporary tiredness.
  • Menstrual changes: spotting or early bleeding.

Serious or Rare Side Effects

  • Allergic reaction: rash, swelling, or difficulty breathing.
  • Severe abdominal pain: possible ectopic pregnancy or other complications.

Precautions & Warnings

Use Norlevo only as directed by a qualified healthcare professional.

  • Hypersensitivity: avoid if known allergy to levonorgestrel or tablet excipients.
  • Timing: consider menstrual cycle phase; effectiveness declines with delayed intake.
  • Not a regular method: do not substitute for ongoing contraceptive regimens.
  • Pregnancy suspicion: seek medical advice if pregnancy is already established.
  • Vomiting: if vomiting occurs within 2 hours, consult a clinician for possible re‑dosing.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Levonorgestrel may interact with other medicines that affect its metabolism or contraceptive efficacy.

Major Interactions (Avoid)

  • Rifampicin: induces hepatic enzymes, reducing levonorgestrel effectiveness.
  • Anticonvulsants (e.g., carbamazepine, phenytoin): lower drug levels, compromising efficacy.
  • St. John’s wort: herbal enzyme inducer that can diminish contraceptive effect.

Moderate Interactions (Monitor Closely)

  • Hormonal contraceptives: concurrent use may reduce overall contraceptive protection.
  • Antifungal azoles (e.g., ketoconazole): may increase levonorgestrel concentrations.
  • Antiretroviral protease inhibitors: can alter drug metabolism, requiring clinical monitoring.

Frequently Asked Questions

Norlevo is an oral emergency contraceptive tablet containing levonorgestrel. It is used to prevent pregnancy after unprotected sexual intercourse or when a regular contraceptive method fails, provided it is taken as soon as possible, ideally within 72 hours.

Levonorgestrel acts primarily by binding to progesterone receptors, suppressing the luteinizing hormone surge and thereby preventing or delaying ovulation. It may also modify tubal motility and endometrial lining, reducing the chance of fertilization and implantation if ovulation has already occurred.

The specific dosing regimen for Norlevo is determined by the prescribing clinician based on regulatory guidelines and the timing of exposure. Healthcare professionals select the appropriate tablet strength and timing to achieve optimal efficacy.

Norlevo is intended for use before pregnancy is established; it is not indicated for treatment of an existing pregnancy. Limited systemic exposure occurs during breastfeeding, and most guidelines consider occasional use compatible with nursing, but a clinician should be consulted.

To order Norlevo, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative to levonorgestrel‑based emergency contraception is ulipristal acetate, a selective progesterone receptor modulator. Ulipristal remains effective up to 120 hours after exposure, whereas levonorgestrel is most effective within 72 hours. Both are oral tablets, but their mechanisms and efficacy windows differ.

Norlevo tablets should be stored at ambient temperature, below 25 °C. Keep them in the original blister pack, protect from moisture, direct sunlight and excessive heat. Do not use tablets that appear discolored or damaged.

Norlevo is taken orally as a single tablet (or as directed by a clinician) with a glass of water. It should be swallowed whole, not chewed, and taken as soon as possible after the qualifying sexual activity.

Serious adverse events are rare but include severe allergic reactions such as rash, swelling, or breathing difficulty, and severe abdominal pain that may indicate an ectopic pregnancy. If any of these occur, seek immediate medical attention.

Norlevo should be avoided by individuals with a known hypersensitivity to levonorgestrel or any tablet excipients, by women who are already pregnant, and by those with severe liver disease without medical supervision. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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