Product image of Normofundin G-5 (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Glu) supplied by GNH India

Normofundin G-5

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Glu
Origin:
EU

Normofundin G-5 (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Glu)

Magnesium Chloride Hexahydrate, the active ingredient in Normofundin G-5, is an electrolyte solution presented as an intravenous solution for intravenous use. It supplies essential sodium, potassium, calcium, magnesium and glucose to restore electrolyte balance and plasma volume in patients requiring fluid and electrolyte replacement.

GNH India supplies Normofundin G-5 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant distribution to healthcare facilities across multiple regions efficiently globally.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
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Indications & Clinical Uses

Normofundin G-5 is an intravenous electrolyte solution used to correct fluid and electrolyte disturbances.

  • Electrolyte replacement: restores sodium, potassium, calcium, magnesium and glucose to maintain plasma volume and electrolyte balance.
  • Fluid resuscitation: rapidly expands intravascular volume in patients with hypovolemia or shock.
  • Hypokalemia: supplies potassium to correct low serum potassium levels.
  • Hypomagnesemia: provides magnesium to treat deficient magnesium concentrations.
  • Hypocalcemia: delivers calcium to normalize serum calcium when deficient.

How It Works

  • Normofundin G-5 delivers a balanced mixture of sodium, potassium, calcium, magnesium ions and glucose directly into the bloodstream. The ions replenish extracellular fluid electrolytes, support cellular membrane potential, and participate in enzymatic reactions, while glucose provides an osmotic driver that facilitates fluid distribution and energy supply, collectively restoring plasma volume and electrolyte homeostasis.

Side Effects

Common Side Effects

  • Infusion site irritation: redness, pain or phlebitis at the catheter site.
  • Mild hypernatremia: slight increase in serum sodium levels.
  • Transient hypotension: temporary drop in blood pressure during rapid infusion.
  • Electrolyte shift symptoms: tingling or muscle cramps.

Serious or Rare Side Effects

  • Severe hyperkalemia: dangerous elevation of potassium causing cardiac arrhythmia.
  • Hypermagnesemia: excessive magnesium leading to respiratory depression.
  • Anaphylactoid reaction: sudden hypersensitivity with rash, bronchospasm or hypotension.
  • Fluid overload: pulmonary edema or heart failure in susceptible patients.

Precautions & Warnings

Normofundin G-5 should be used with clinical monitoring and appropriate patient assessment.

  • Renal impairment: monitor serum electrolytes closely to avoid accumulation.
  • Cardiac disease: assess cardiac function before rapid volume expansion.
  • Electrolyte disorders: correct existing imbalances prior to infusion.
  • Concomitant electrolyte therapy: avoid duplicate dosing that may cause overload.
  • Store below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Normofundin G-5 may interact with other medications that affect electrolyte balance.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics: risk of severe hyperkalemia.
  • Calcium channel blockers: may potentiate calcium‑related cardiac effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor potassium and renal function.
  • Digoxin: altered potassium levels can affect digoxin toxicity.
  • Loop diuretics: may require adjustment of electrolyte replacement dosing.

Frequently Asked Questions

Normofundin G-5 is an intravenous electrolyte solution indicated for fluid resuscitation, electrolyte replacement, and the correction of specific deficiencies such as hypokalemia, hypomagnesemia and hypocalcemia in patients who require rapid restoration of plasma volume and electrolyte balance.

Magnesium chloride provides magnesium ions that act as cofactors for many enzymatic reactions, help stabilize cell membranes, and contribute to normal neuromuscular function. In the context of the solution, it works together with sodium, potassium, calcium and glucose to re‑establish physiological electrolyte concentrations.

The dose of Normofundin G-5 is individualized. The prescribing clinician determines the volume and rate of infusion based on the patient’s electrolyte status, fluid needs, weight, renal function and clinical condition. No fixed regimen is provided in the product information.

Safety data for Normofundin G-5 in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Normofundin G-5, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Normofundin G-5 contains a balanced mix of sodium, potassium, calcium, magnesium and glucose, similar to other balanced crystalloids such as Ringer’s Lactate or Plasmalyte. Its specific composition may be preferred when additional magnesium or calcium supplementation is required, whereas alternatives may have different buffer systems or ion concentrations.

Store Normofundin G-5 below 25 °C in its original packaging. Protect the solution from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze. Inspect the container for leaks or discoloration before use.

Normofundin G-5 is administered intravenously. It is typically infused through a peripheral or central venous catheter using a calibrated infusion set. The rate and total volume are set by the prescriber according to the patient’s clinical needs and monitored throughout the infusion.

Serious risks include severe hyperkalemia or hypermagnesemia, which can cause cardiac arrhythmias, respiratory depression, or cardiac arrest. Fluid overload leading to pulmonary edema and anaphylactoid reactions are also critical concerns that require immediate medical attention.

Normofundin G-5 is contraindicated in patients with known hypersensitivity to any component, untreated severe hyperkalemia, hypermagnesemia, hypercalcemia, or in those with severe renal failure where electrolyte accumulation cannot be safely managed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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