Product image of Noscaflex Expectorans (Noscapine Hydrochloride, Guaifenesin) supplied by GNH India

Noscaflex Expectorans

Active Ingredient:
Noscapine Hydrochloride, Guaifenesin
Origin:
EU

Noscaflex Expectorans (Noscapine Hydrochloride, Guaifenesin)

Noscapine Hydrochloride, the active ingredient in Noscaflex Expectorans, is an antitussive presented as an oral dosage form for oral use. It is combined with guaifenesin to relieve cough and aid mucus clearance in adults and children.
GNH India supplies Noscaflex Expectorans as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharinex

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Indications & Clinical Uses

Noscaflex Expectorans, containing noscapine hydrochloride and guaifenesin, is used to manage cough and chest congestion.

  • Acute cough: reduces the frequency and intensity of coughing episodes.
  • Chest congestion: helps loosen and thin mucus in the airways.
  • Facilitation of mucus clearance: promotes expectoration of bronchial secretions.

How It Works

  • Noscapine hydrochloride acts centrally on the cough centre, likely via sigma‑receptor modulation, to suppress the cough reflex. Guaifenesin increases the volume of airway surface liquid and decreases mucus viscosity, enhancing mucociliary clearance and facilitating expectoration.

Side Effects

Common Side Effects

  • Nausea: mild stomach upset may occur.
  • Dizziness: transient light‑headedness reported.
  • Headache: occasional mild headache.
  • Gastrointestinal discomfort: mild abdominal pain or indigestion.
  • Mild rash: skin irritation in some users.

Serious or Rare Side Effects

  • Allergic reactions: including swelling, itching, or anaphylaxis.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.
  • Respiratory depression: rare, especially with excessive dosing.
  • Hepatic enzyme elevation: uncommon liver function changes.
  • Hematuria: rare blood in urine.

Precautions & Warnings

Before using Noscaflex Expectorans, consider the following precautions:

  • Use in children: follow prescriber guidance for age‑appropriate dosing.
  • Pregnancy: safety not established; consult a healthcare professional.
  • Breastfeeding: unknown excretion; discuss risks with a clinician.
  • Concomitant CNS depressants: monitor for additive sedation.
  • Renal or hepatic impairment: dose adjustment may be required.
  • Store below 25°C: keep in the original packaging, protect from moisture.

Avoid Interactions

Noscaflex Expectorans may interact with other medications as follows:

Major Interactions (Avoid)

  • Other central cough suppressants: risk of excessive sedation or cough suppression.
  • Monoamine oxidase inhibitors: potential for unpredictable central effects.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance drowsiness.
  • Sedating antihistamines: increase likelihood of dizziness.
  • Certain antihypertensives: guaifenesin may affect blood pressure control.
  • Anticoagulants: monitor for any changes in bleeding risk.

Frequently Asked Questions

Noscaflex Expectorans is an over‑the‑counter oral medication that combines noscapine hydrochloride and guaifenesin to relieve acute cough, reduce chest congestion, and help clear mucus from the airways.

Noscapine hydrochloride acts on the central cough centre, likely through sigma‑receptor modulation, which dampens the cough reflex and reduces the urge to cough without causing significant sedation.

The appropriate dose of Noscaflex Expectorans is determined by a qualified prescriber based on the patient’s age, weight, and clinical condition. Patients should follow the healthcare professional’s instructions and the product label.

Safety data for noscapine hydrochloride and guaifenesin in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using this product.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Unlike single‑ingredient cough suppressants, Noscaflex Expectorans combines an antitussive (noscapine) with an expectorant (guaifenesin), offering both cough reduction and mucus clearance, which can be advantageous for patients with productive coughs.

Store the product below 25 °C in its original container, protecting it from moisture and direct sunlight. Keep it out of reach of children and do not use after the expiration date.

Noscaflex Expectorans is taken orally, usually with a full glass of water. It can be taken with or without food, unless the prescribing information advises otherwise.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, and respiratory depression. Patients should seek immediate medical attention if they experience swelling, rash, difficulty breathing, or any unexpected severe symptoms.

Individuals with known hypersensitivity to noscapine, guaifenesin, or any excipients in the formulation should avoid this product. It should also be used with caution in patients taking other central cough suppressants or those with significant liver or kidney disease, after consulting a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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