Notus Antitusivo (Dextromethorphan Hydrobromide)

Dextromethorphan suppresses cough by acting on the medullary cough centre. It blocks NMDA receptors and stimulates sigma‑1 receptors, which together reduce the neuronal signalling that initiates the cough reflex, providing a central, non‑opioid cough‑suppressing effect.

The appropriate dose is determined by a healthcare professional based on the individual’s age, weight, and clinical situation. Over‑the‑counter products typically follow label instructions, but the prescriber should confirm the exact regimen for each patient.

Safety data for Dextromethorphan in pregnancy and lactation are limited. It is classified as a category where risk cannot be ruled out, so use only if the potential benefit justifies the potential risk to the fetus or infant, and after consulting a healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with opioid‑based cough suppressants such as codeine, Dextromethorphan offers a non‑opioid mechanism, lower risk of dependence, and fewer respiratory depressant effects. However, it may interact with serotonergic drugs, a consideration less prominent with pure opioid agents.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and heat sources. Ensure the container is tightly closed to maintain product stability.

The medication is taken orally. Swallow the tablet whole with a glass of water; do not crush, chew, or split unless instructed by a healthcare professional. It is usually taken as needed for cough relief, following the dosage guidance provided by the prescriber.

Serious adverse reactions, though rare, include allergic responses such as rash or angioedema, serotonin syndrome when combined with serotonergic agents, severe respiratory depression in overdose, and rare neurological effects like hallucinations or seizures. Prompt medical attention is required if any of these occur.

Individuals who should avoid this product include children under four years of age, patients currently taking monoamine oxidase inhibitors, those with known hypersensitivity to Dextromethorphan, and persons with severe hepatic impairment unless advised otherwise by a physician.