Product image of Novial (Desogestrel, Ethinylestradiol) supplied by GNH India

Novial

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Novial (Desogestrel, Ethinylestradiol)

Desogestrel/Ethinylestradiol, the active ingredients in Novial, are a combined oral contraceptive presented as a tablet for oral use. They are prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age.

GNH India supplies Novial as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards, manufactures under EU GMP guidelines, and provides reliable global distribution to authorized healthcare providers.

Manufacturer / TM Owner

Aspen Pharma Trading Limited

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Indications & Clinical Uses

Novial, a combined oral contraceptive, is used in the hormonal management of reproductive health.

  • Contraception: prevents pregnancy by inhibiting ovulation and altering cervical mucus.
  • Menstrual cycle regulation: helps achieve more regular and predictable periods.
  • Acne management: may reduce acne associated with hormonal fluctuations.
  • Endometriosis symptom relief: can lessen menstrual pain and suppress lesion growth.

How It Works

  • Desogestrel and ethinylestradiol act together to suppress the hypothalamic‑pituitary‑gonadal axis, reducing the secretion of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH). This inhibition prevents follicular development and ovulation. The progestogenic component also thickens cervical mucus and induces endometrial changes that hinder sperm penetration and implantation, providing effective contraceptive protection.

Side Effects

Novial may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Nausea: transient stomach upset, often improves with continued use.
  • Breast tenderness: mild swelling or discomfort of the breasts.
  • Headache: occasional mild to moderate headache.
  • Spotting: irregular bleeding between periods.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in deep veins, typically in the legs.
  • Pulmonary embolism: clot migration to the lungs, a medical emergency.
  • Severe allergic reaction: rash, swelling, or anaphylaxis requiring immediate care.
  • Liver dysfunction: jaundice or abnormal liver enzyme levels.

Precautions & Warnings

Before prescribing Novial, clinicians should evaluate individual risk factors and counsel patients on safe use.

  • Assess thromboembolic risk: evaluate personal and family history of clotting disorders.
  • Avoid smoking: especially in women over 35 years of age.
  • Monitor blood pressure: hypertension may increase cardiovascular risk.
  • Review liver function: contraindicated in active liver disease.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Novial can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin, rifampin): may markedly reduce contraceptive efficacy.
  • Certain antiretrovirals (e.g., ritonavir): can increase risk of thrombotic events.

Moderate Interactions (Monitor Closely)

  • St. John’s wort: may lower hormone levels and reduce effectiveness.
  • SSRIs (e.g., fluoxetine): may increase risk of bleeding.
  • Diuretics (e.g., thiazides): may affect potassium balance and blood pressure.

Frequently Asked Questions

Novial is a combined oral contraceptive that is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age. It works by inhibiting ovulation and altering cervical mucus, providing reliable hormonal birth control.

The two hormones in Novial suppress the release of luteinizing hormone and follicle‑stimulating hormone from the pituitary gland, which stops ovulation. Desogestrel also thickens cervical mucus, while ethinylestradiol modifies the endometrium, making it less suitable for implantation.

The dosing regimen for Novial is determined by the prescribing healthcare professional. Typically, it is taken as a daily tablet according to a specific cycle, but the exact schedule and number of tablets should follow the prescriber’s instructions.

Novial is intended for use only when pregnancy is not desired. It should not be started during an existing pregnancy, and women who become pregnant should discontinue use. Safety during breastfeeding has not been fully established, so a healthcare provider should be consulted.

To order Novial, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Novial contains the same hormone combination (desogestrel and ethinylestradiol) found in many other combined oral contraceptives. Its efficacy, safety profile and side‑effect spectrum are comparable to other products in the class, with differences mainly in dosage strengths and brand‑specific excipients.

Novial tablets should be stored at ambient temperature, below 25 °C, in their original packaging. They must be kept away from moisture, direct sunlight and excessive heat to maintain potency throughout the shelf life.

Novial is taken orally as a tablet, usually once daily at the same time each day. The typical regimen follows a 21‑day active tablet phase followed by a 7‑day placebo or hormone‑free interval, but patients should follow the schedule prescribed by their clinician.

The most serious risks include thromboembolic events such as deep vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. These risks are higher in women who smoke, are over 35, or have a history of clotting disorders, and they require immediate medical attention if symptoms appear.

Novial is contraindicated in women with a history of thromboembolic disease, active liver disease, known or suspected breast cancer, uncontrolled hypertension, or those who are pregnant. It should also be avoided by smokers over 35 years of age and by anyone taking interacting medications without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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