Product image of Novynette (Desogestrel, Ethinylestradiol) supplied by GNH India

Novynette

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Novynette (Desogestrel, Ethinylestradiol)

Desogestrel, Ethinylestradiol, the active ingredients in Novynette, are a combined oral contraceptive presented as a 0.075 mg desogestrel/0.02 mg ethinylestradiol tablet for oral use. It prevents pregnancy and regulates menstrual cycles in women of reproductive age.

GNH India supplies Novynette as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Novynette is manufactured under EU GMP guidelines and is exported to multiple regions, ensuring consistent product quality and regulatory compliance.

Manufacturer / TM Owner

Gedeon Richter Plc.

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Indications & Clinical Uses

Novynette, a combined oral contraceptive, acts on the hormonal regulation pathway to prevent pregnancy and manage menstrual disorders.

  • Contraception: provides reliable prevention of pregnancy in women of reproductive age.
  • Menstrual cycle regulation: helps achieve regular, predictable menstrual periods.
  • Acne treatment: reduces acne lesions associated with hormonal fluctuations.

How It Works

  • Desogestrel is a progestogenic agent that suppresses the mid‑cycle luteinizing hormone surge, while ethinylestradiol provides estrogenic feedback that stabilizes the endometrium and enhances negative feedback on gonadotropins. Together they inhibit ovulation, thicken cervical mucus, and alter the endometrial lining, creating multiple barriers to fertilisation and implantation.

Side Effects

Novynette may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: occasional mild stomach upset.
  • Breast tenderness: temporary swelling or discomfort.
  • Headache: mild to moderate intensity.
  • Breakthrough bleeding: spotting between periods.
  • Mood changes: irritability or mild mood swings.
  • Weight gain: slight increase in body weight.

Serious or Rare Side Effects

  • Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.
  • Arterial thrombosis: stroke or myocardial infarction.
  • Hypertension: new‑onset high blood pressure.
  • Liver tumor: benign hepatic adenoma.
  • Severe allergic reaction: anaphylaxis or angioedema.

Precautions & Warnings

Before prescribing Novynette, clinicians should evaluate individual risk factors and counsel patients on safety considerations.

  • Assess cardiovascular risk: review history of thrombosis, smoking, hypertension, and obesity.
  • Contraindicated in pregnancy: avoid use if pregnancy is known or suspected.
  • Monitor blood pressure: check for new or worsening hypertension.
  • Consider hepatic function: use with caution in liver disease.
  • Review concomitant medications: assess for drugs that may reduce efficacy.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Novynette can interact with several medicines, altering its effectiveness or increasing adverse risk.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): may reduce contraceptive efficacy.
  • St. John's wort: strong CYP3A4 inducer that can lower hormone levels.
  • Anticoagulants (e.g., warfarin): may increase risk of thrombosis.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: hormonal changes may affect blood pressure control.
  • Selective serotonin reuptake inhibitors: may exacerbate mood‑related side effects.
  • Diuretics: potential electrolyte disturbances when combined with hormonal therapy.

Frequently Asked Questions

Novynette is a combined oral contraceptive containing desogestrel and ethinylestradiol. It is prescribed to prevent pregnancy, regulate menstrual cycles, and treat hormone‑related acne in women of reproductive age.

Desogestrel acts as a progestogen that suppresses the luteinising hormone surge, while ethinylestradiol provides estrogenic feedback that stabilises the endometrium and reinforces negative feedback on gonadotropins. Together they inhibit ovulation, thicken cervical mucus, and alter the uterine lining, creating multiple barriers to fertilisation and implantation.

The dosing regimen for Novynette is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and any missed‑dose instructions should follow the prescriber’s guidance.

Novynette is contraindicated in known or suspected pregnancy and should not be started during pregnancy. It is generally not recommended for breastfeeding women because hormonal contraceptives can affect milk production; a healthcare provider should evaluate alternative options.

To order Novynette, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Novynette contains desogestrel, a third‑generation progestogen, which may offer a lower incidence of androgenic side effects such as acne compared with older progestins. Its efficacy in preventing pregnancy is comparable to other combined oral contraceptives, but individual tolerability and risk profiles can differ.

Novynette tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Novynette is taken orally as a tablet. The usual regimen is one tablet each day, preferably at the same time, for 21 consecutive days followed by a hormone‑free interval (typically 7 days) during which withdrawal bleeding occurs.

The most serious risks include venous or arterial thromboembolism (blood clots), stroke, myocardial infarction, and severe hypertension. Patients with a history of clotting disorders, smoking, or certain cardiovascular conditions should be evaluated carefully before starting therapy.

Novynette should not be used by women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or are smokers aged 35 years or older. Contraindications are detailed in the product’s prescribing information.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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