Product image of Nubeqa (Darolutamide) supplied by GNH India

Nubeqa

Active Ingredient:
Darolutamide
Origin:
EU

Nubeqa (Darolutamide)

Darolutamide, the active ingredient in Nubeqa, is an androgen receptor antagonist presented as a tablet for oral use. It treats non‑metastatic castration‑resistant prostate cancer in men who have previously received androgen‑deprivation therapy. GNH India supplies Nubeqa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

GNH India supplies Nubeqa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Bayer Ag

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Indications & Clinical Uses

Nubeqa is an androgen‑receptor targeting therapy indicated for prostate‑cancer related indications.

  • Non‑metastatic castration‑resistant prostate cancer (nmCRPC): delays metastasis and improves overall survival.
  • Metastatic castration‑resistant prostate cancer (mCRP​C): used in combination with androgen‑deprivation therapy to extend progression‑free survival.
  • High‑risk high‑grade prostate cancer: provides additional hormonal control when standard ADT is insufficient.
  • Post‑surgical resection of prostate tumour tissue in select patients: helps maintain low testosterone levels.
  • Advanced treatment resistant prostate cancer cases where other AR‑ ant­​s­​trogens have failed.

How It Works

  • Darolutamide binds selectively to the ligand‑binding domain of the androgen receptor, preventing activation by testosterone and dihydrotestosterone. This blockade stops the receptor from moving to the cell nucleus and from regulating genes that drive prostate‑cancer cell growth and survival, thereby inhibiting tumor progression.

Side Effects

Common Side Effects

  • Fatigue 
  • Di­ t ​    ​       …

Serious or Rare Side Effects

-  ...  

Precautions & Warnings

  • Nucle    

Avoid Interactions

  • Major  

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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