Product image of Numeta G13e (Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio) supplied by GNH India

Numeta G13e

Active Ingredient:
Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio
Origin:
EU

Numeta G13e (Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio)

Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methionine, the active ingredients in Numeta G13e, are a parenteral nutrition presented as an amino acid solution for intravenous use. It supports nutritional needs in patients who cannot receive adequate enteral nutrition, such as post‑operative or critically ill patients.

GNH India supplies Numeta G13e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Baxter Medical Ab

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Indications & Clinical Uses

Numeta G13e is used in the clinical setting to address protein and energy deficits when oral or enteral intake is insufficient.

  • Inadequate enteral nutrition: provides essential amino acids to meet daily protein requirements.
  • Post‑operative patients: supports wound healing and tissue repair through amino acid supplementation.
  • Critical care patients: helps maintain nitrogen balance and metabolic stability during severe illness.

How It Works

  • Numeta G13e delivers a balanced mixture of essential and non‑essential amino acids directly into the bloodstream. These amino acids serve as substrates for protein synthesis, replenish nitrogen stores, and support metabolic pathways involved in tissue repair, immune function, and energy production, thereby compensating for deficits when enteral nutrition is unavailable or inadequate.

Side Effects

Numeta G13e may be associated with a range of infusion‑related reactions.

Common Side Effects

  • Hyperglycemia: elevated blood glucose levels during infusion.
  • Electrolyte imbalance: mild shifts in potassium, sodium, or calcium.
  • Infusion site phlebitis: irritation or inflammation at the catheter site.
  • Nausea or mild gastrointestinal discomfort.
  • Transient fever or chills.
  • Metabolic alkalosis: slight increase in blood pH.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate intervention.
  • Severe hypernatremia or hyperkalemia: dangerous electrolyte elevations.
  • Acute renal dysfunction: impaired kidney function during therapy.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Severe metabolic acidosis: significant drop in blood pH.
  • Catheter‑related bloodstream infection: systemic infection linked to the infusion line.

Precautions & Warnings

Before initiating Numeta G13e, clinicians should evaluate patient‑specific factors and monitor therapy closely.

  • Renal function assessment: adjust infusion rate in patients with impaired kidney function.
  • Electrolyte monitoring: check serum potassium, sodium, calcium, and magnesium regularly.
  • Blood glucose control: monitor glucose levels, especially in diabetic patients.
  • Hepatic status review: consider dose modification if liver dysfunction is present.
  • Aseptic technique: ensure sterile handling to prevent catheter‑related infections.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Numeta G13e can interact with other intravenous agents and systemic medications.

Major Interactions (Avoid)

  • High‑dose potassium supplements: risk of hyperkalemia when combined.
  • Calcium gluconate solutions: potential precipitation with amino acids.
  • Concurrent parenteral nutrition admixtures: incompatibility may cause precipitation or loss of efficacy.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may exacerbate electrolyte shifts; monitor serum levels.
  • Insulin therapy: increased risk of hypoglycemia; adjust glucose monitoring.
  • Anticoagulants: catheter manipulation may increase bleeding risk; observe coagulation parameters.

Frequently Asked Questions

Numeta G13e is an intravenous amino acid solution used to provide essential and non‑essential amino acids to patients who cannot meet their nutritional needs through oral or enteral routes, such as those in post‑operative care, intensive care, or with severe malabsorption.

The blend supplies substrates for protein synthesis, helps maintain nitrogen balance, and supports metabolic pathways involved in tissue repair, immune function, and energy production, thereby compensating for deficits when normal dietary intake is insufficient.

The prescribed dose of Numeta G13e is determined by the treating physician based on the patient’s weight, clinical condition, and laboratory parameters. Dosing is individualized and should follow the prescriber’s instructions.

Safety data for Numeta G13e in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and required import documentation.

Numeta G13e offers a comprehensive amino acid profile that closely matches the composition of human plasma proteins, providing balanced essential and non‑essential amino acids. Compared with simpler amino acid solutions, it may reduce the need for additional supplementation and better support metabolic demands in critically ill patients.

Numeta G13e must be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before use, inspect for particulate matter or discoloration and ensure aseptic technique during preparation.

The product is administered intravenously, typically via a central or peripheral venous catheter. Infusion rates are set according to the prescribing clinician’s orders, and the solution should be infused over the recommended period while monitoring the patient’s vital signs and laboratory values.

Serious risks include anaphylactic reactions, severe electrolyte disturbances (such as hyperkalemia or hypernatremia), acute renal or hepatic dysfunction, and catheter‑related bloodstream infections. Prompt recognition and management of these events are essential.

Numeta G13e should be avoided in patients with known hypersensitivity to any of its amino acid components, those with uncontrolled severe electrolyte imbalances, or individuals for whom intravenous nutrition is contraindicated. Clinical judgment is required for patients with severe organ dysfunction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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