Product image of Numetzah G16%e (Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio) supplied by GNH India

Numetzah G16%e

Active Ingredient:
Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio
Origin:
EU

Numetzah G16%e (Valine, Ornithine Hydrochloride, Alanine, Arginine, Cysteine, Histidine, Isoleucine, Leucine, Methio)

Valine, the active ingredient in Numetzah G16%e, is a unknown presented as a unknown/unknown for intravenous use. It is employed in clinical settings where amino acid supplementation is indicated, such as parenteral nutrition and metabolic support.
GNH India supplies Numetzah G16%e as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Baxter Sa

1
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Indications & Clinical Uses

Numetzah G16%e provides intravenous amino acids for patients requiring parenteral nutrition and metabolic support.

  • Parenteral nutrition: supplies essential amino acids to support protein synthesis in patients unable to eat orally.
  • Metabolic support: assists in maintaining nitrogen balance during catabolic states such as trauma or surgery.
  • Liver disease management: may help reduce ammonia production in hepatic encephalopathy when used under medical supervision.

How It Works

  • The amino acids in Numetzah G16%e act as substrates for protein synthesis, replenish essential nitrogen pools, and support cellular metabolism. Intravenous delivery bypasses gastrointestinal absorption, rapidly increasing plasma amino acid concentrations, which can enhance tissue repair, modulate immune function, and improve nitrogen balance in critically ill patients.

Side Effects

Common Side Effects

  • Nausea or vomiting: mild gastrointestinal discomfort during infusion.
  • Hyperglycemia: transient rise in blood glucose levels, especially in diabetic patients.
  • Electrolyte imbalance: shifts in potassium, sodium, or calcium levels.
  • Infusion site reactions: redness, warmth, or mild pain at the injection site.
  • Headache: transient mild headache during or after infusion.
  • Mild hypotension: temporary drop in blood pressure.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Severe hyperammonemia: elevated ammonia levels in patients with compromised liver function.
  • Metabolic acidosis: significant pH changes in the blood.
  • Renal dysfunction: impaired kidney function in susceptible individuals.
  • Thrombophlebitis: inflammation and clot formation in the vein used for infusion.
  • Severe electrolyte disturbances: dangerous shifts in potassium or calcium that may affect cardiac rhythm.

Precautions & Warnings

Numetzah G16%e should be administered with careful clinical monitoring.

  • Renal impairment: assess renal function and adjust infusion rate as needed.
  • Liver disease: monitor ammonia levels and liver enzymes closely.
  • Electrolyte disorders: check serum electrolytes before and during therapy.
  • Hyperglycemia risk: monitor blood glucose, especially in diabetic patients.
  • Hypersensitivity: evaluate patient history for known amino acid or excipient allergies.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Numetzah G16%e may interact with other therapies that affect electrolyte or metabolic balance.

Major Interactions (Avoid)

  • High-dose potassium supplements: risk of hyperkalemia.
  • Concurrent insulin therapy: may potentiate hypoglycemia.
  • Other parenteral nutrition solutions: can cause nutrient overload.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may exacerbate electrolyte shifts.
  • Renal replacement therapy: alters amino acid clearance, requiring dose adjustment.
  • Anticoagulants: increased risk of bleeding at infusion sites.

Frequently Asked Questions

Numetzah G16%e is an intravenous amino acid formulation used to provide essential building blocks for protein synthesis in patients who cannot receive nutrition orally. It supports parenteral nutrition, helps maintain nitrogen balance during catabolic states, and may be employed as part of metabolic support in critical care settings.

Valine, together with the other amino acids in the product, serves as a substrate for protein synthesis and cellular metabolism. When delivered intravenously, it quickly raises plasma amino acid levels, facilitating tissue repair, supporting immune function, and contributing to overall nitrogen balance in the body.

The dose of Numetzah G16%e is determined by the prescribing clinician based on the patient’s weight, clinical condition, and nutritional requirements. Healthcare professionals calculate the appropriate infusion rate and total daily amount to meet individual therapeutic goals.

Safety of Numetzah G16%e in pregnancy or while breastfeeding has not been fully established. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Numetzah G16%e, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Numetzah G16%e contains a specific blend of essential and conditionally essential amino acids, similar to other parenteral amino acid formulations. Differences may lie in the exact composition, concentration, and manufacturing standards. Clinicians choose a product based on the patient’s nutritional needs, compatibility with other IV fluids, and regulatory approvals.

Numetzah G16%e must be stored at 2‑8 °C, protected from light, and kept in its original packaging. It should not be frozen or shaken vigorously. Prior to administration, allow the product to reach room temperature if required by the infusion protocol, and inspect for any particulate matter or discoloration.

Numetzah G16%e is administered intravenously by a qualified healthcare professional. The solution is typically infused through a peripheral or central venous line, using an infusion pump or gravity drip, according to the prescribed rate and total daily volume. Monitoring of vital signs and laboratory parameters is recommended during therapy.

Serious risks include anaphylactic reactions, severe electrolyte disturbances, metabolic acidosis, hyperammonemia in patients with liver dysfunction, and renal impairment. Prompt recognition of these events and immediate medical intervention are essential. Regular laboratory monitoring helps mitigate these risks.

Numetzah G16%e should be avoided in patients with known hypersensitivity to any of its amino acid components, severe uncontrolled electrolyte abnormalities, or untreated severe renal or hepatic failure unless closely monitored. Contraindications are determined by the treating physician based on individual patient factors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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