Product image of Nuralgan (Ibuprofen, Paracetamol) supplied by GNH India

Nuralgan

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Nuralgan (Ibuprofen, Paracetamol)

Ibuprofen and Paracetamol, the active ingredients in Nuralgan, are an NSAID and an analgesic/antipyretic presented as an oral dosage form for oral use. They are combined to provide relief from mild to moderate pain and reduce fever in adults and children when appropriate.

GNH India supplies Nuralgan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Smb S.A.

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Indications & Clinical Uses

Nuralgan combines ibuprofen and paracetamol to act on inflammatory and pain pathways, offering relief for several common conditions.

  • Mild to moderate pain: reduces discomfort from dental, postoperative or injury‑related pain.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Headache: alleviates tension‑type and mild migraine symptoms.
  • Musculoskeletal pain: eases aches from strains, sprains or arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis and reducing inflammation and peripheral pain signals. Paracetamol acts centrally, likely inhibiting COX activity in the brain and modulating serotonergic pathways, leading to antipyretic and analgesic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild transient headache may occur.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated liver enzymes: transient increase in laboratory values.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Hepatotoxicity: marked liver injury, especially with overdose.
  • Renal impairment: acute kidney injury in susceptible individuals.
  • Blood disorders: thrombocytopenia or neutropenia.

Precautions & Warnings

Before using Nuralgan, consider the following precautions:

  • Assess renal function: avoid in severe renal impairment.
  • Evaluate hepatic status: use with caution in liver disease.
  • Review gastrointestinal history: avoid in active ulcer or bleeding.
  • Monitor for hypersensitivity: discontinue if rash or swelling develops.
  • Avoid concurrent NSAIDs: increase risk of GI and renal events.
  • Store at ambient temperature: keep below 25°C, protect from moisture and keep in original packaging.

Avoid Interactions

Nuralgan may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Hepatotoxic drugs (e.g., isoniazid, methotrexate): amplified liver injury.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in renal function.
  • Antihypertensives: ibuprofen may blunt blood pressure control.
  • Lithium: ibuprofen may raise serum lithium levels.

Frequently Asked Questions

Nuralgan is a combination of ibuprofen and paracetamol used to relieve mild to moderate pain and to reduce fever. It is commonly prescribed for conditions such as headaches, musculoskeletal aches, dental pain, and febrile illnesses.

Ibuprofen blocks cyclooxygenase enzymes, lowering prostaglandin production and reducing inflammation and peripheral pain signals. Paracetamol acts mainly in the central nervous system, inhibiting prostaglandin synthesis and modulating pain pathways, providing antipyretic and analgesic effects.

The appropriate dose of Nuralgan is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and other medications. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of Nuralgan in pregnancy or while breastfeeding should be evaluated by a qualified healthcare provider. Ibuprofen may be avoided in the third trimester, and paracetamol is generally considered safer, but professional guidance is essential.

To order Nuralgan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Nuralgan combines the anti‑inflammatory action of ibuprofen with the central analgesic and antipyretic effects of paracetamol, potentially offering broader pain relief and fever control than either agent alone. However, combined therapy may increase the risk of certain side effects, so clinical judgment is required.

Nuralgan should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture. Keep the product out of reach of children and avoid exposure to direct sunlight.

Nuralgan is taken orally, usually with a glass of water. It may be taken with or without food, depending on the prescriber’s advice, to minimize gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, significant liver injury (hepatotoxicity), and acute kidney injury, especially in patients with pre‑existing renal or hepatic disease.

Individuals with known hypersensitivity to ibuprofen, paracetamol, or any component of the formulation, those with active gastrointestinal bleeding, severe liver or kidney disease, and patients on anticoagulant therapy without medical supervision should avoid using Nuralgan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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