Product image of Nuralgan (Ibuprofen, Paracetamol) supplied by GNH India

Nuralgan

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Nuralgan (Ibuprofen, Paracetamol)

Ibuprofen and Paracetamol, the active ingredients in Nuralgan, are non‑steroidal anti‑inflammatory and analgesic/antipyretic agents presented as oral tablets for systemic use. They relieve mild to moderate pain and reduce fever in adults and children as directed.

GNH India supplies Nuralgan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Smb S.A.

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Indications & Clinical Uses

Nuralgan, a combination of ibuprofen and paracetamol, provides analgesic and antipyretic effects for several common conditions.

  • Headache: reduces pain intensity and associated discomfort.
  • Fever: lowers elevated body temperature.
  • Musculoskeletal pain: alleviates pain and inflammation in muscles and joints.
  • Dental pain: eases postoperative or acute toothache.
  • Menstrual cramps: diminishes uterine cramp pain.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing peripheral prostaglandin synthesis and thereby reducing inflammation and pain. Paracetamol acts centrally, inhibiting a variant of COX in the brain and modulating serotonergic pathways, which contributes to analgesia and antipyresis. The combined action provides synergistic relief of pain and fever.

Side Effects

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Dyspepsia: discomfort or burning in the upper abdomen.
  • Dizziness: transient feeling of light‑headedness.
  • Rash: mild skin irritation or redness.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: severe stomach or intestinal bleeding.
  • Liver injury: elevated liver enzymes or hepatitis.
  • Allergic reactions: anaphylaxis, swelling, or severe rash.
  • Renal impairment: reduced kidney function, especially with prolonged use.

Precautions & Warnings

Before using Nuralgan, consider the following precautions.

  • Pregnancy: avoid in the third trimester unless specifically advised by a healthcare professional.
  • Liver disease: use with caution; monitor hepatic function.
  • Kidney disease: assess renal function and adjust use accordingly.
  • Asthma: may precipitate bronchospasm in susceptible individuals.
  • Concomitant anticoagulants: increased risk of bleeding; monitor coagulation status.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Nuralgan may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • SSRIs (e.g., fluoxetine): increased bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., lisinopril): possible reduction in renal function.
  • Methotrexate: decreased clearance may raise toxicity levels.

Frequently Asked Questions

Nuralgan is a fixed‑dose combination of ibuprofen and paracetamol designed to relieve mild to moderate pain such as headache, musculoskeletal discomfort, dental pain, and menstrual cramps, and to reduce fever. It is commonly used in adults and children when a single agent does not provide sufficient symptom control.

Ibuprofen, one of the active ingredients in Nuralgan, blocks cyclo‑oxygenase enzymes (COX‑1 and COX‑2), which reduces the production of prostaglandins that mediate inflammation, pain, and fever. This inhibition lessens peripheral inflammation and provides analgesic effects.

The appropriate dose of Nuralgan is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and other medications. The prescriber will specify the exact amount and frequency that best meets the therapeutic need.

Use of Nuralgan during pregnancy should be avoided in the third trimester because ibuprofen may affect fetal cardiovascular development. In earlier trimesters, it should only be used if clearly needed and prescribed. Breastfeeding mothers should consult a physician, as both ibuprofen and paracetamol can pass into breast milk in small amounts.

To order Nuralgan, submit an enquiry on the product page at gnhindia.com, providing the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will respond with pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Nuralgan combines ibuprofen’s anti‑inflammatory action with paracetamol’s central analgesic and antipyretic effects, offering broader pain relief and fever reduction than either agent alone. The combination can achieve effective symptom control at lower individual doses, potentially reducing the risk of side effects associated with higher doses of a single drug.

Nuralgan tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and store them out of reach of children.

Nuralgan is administered orally with a full glass of water. It may be taken with or without food, although taking it with food can help reduce stomach irritation. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding, especially in patients with a history of ulcers or who use anticoagulants; liver injury, particularly with excessive paracetamol exposure; severe allergic reactions such as anaphylaxis; and renal impairment in patients with pre‑existing kidney disease or dehydration.

Nuralgan should be avoided in individuals with known hypersensitivity to ibuprofen, paracetamol, or any excipients; those with active peptic ulcer disease; severe liver or kidney impairment; third‑trimester pregnancy; and patients taking other NSAIDs or anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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