Product image of Nurodur (Ibuprofen) supplied by GNH India

Nurodur

Active Ingredient:
Ibuprofen
Origin:
EU

Nurodur (Ibuprofen)

Ibuprofen, the active ingredient in Nurodur, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, reduces fever, and alleviates inflammation in conditions such as arthritis.

GNH India supplies Nurodur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU GMP standards and providing reliable sourcing for global healthcare providers. The company ensures timely delivery, regulatory documentation, and post‑market support across multiple regions.

Manufacturer / TM Owner

Reckitt Benckiser D.O.O.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever, and inflammation by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory processes.
  • Arthritis and other inflammatory conditions: decreases joint swelling and improves mobility in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which are key in the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient headache episodes.
  • Dizziness: light‑headed feeling or vertigo.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Cardiovascular events: increased risk of heart attack or stroke, especially with high‑dose or prolonged use.
  • Severe allergic reactions: anaphylaxis, angioedema, or bronchospasm.

Precautions & Warnings

When using ibuprofen, several precautions should be observed to minimize risk.

  • Assess renal function: avoid use in patients with severe kidney disease or dehydration.
  • Monitor gastrointestinal health: use with caution in individuals with history of ulcers or bleeding.
  • Evaluate cardiovascular risk: limit use in patients with uncontrolled hypertension or known heart disease.
  • Review concomitant medications: check for other NSAIDs, anticoagulants, or corticosteroids that may increase adverse effects.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk.
  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Diuretics: possible reduction in diuretic effectiveness and renal perfusion.
  • Lithium: ibuprofen may raise lithium serum levels, requiring monitoring.

Frequently Asked Questions

Nurodur contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as arthritis, musculoskeletal injuries, and dental discomfort.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels decrease pain signaling, lower fever, and reduce inflammatory swelling.

The appropriate dose of Nurodur is determined by a qualified prescriber based on the individual’s age, condition, and overall health. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. Generally, it is avoided in the third trimester and used only if the benefit outweighs the risk. Breastfeeding mothers should consult a healthcare provider before use.

To order Nurodur, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Both ibuprofen (Nurodur) and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen offers longer duration of action. Choice between them depends on clinical response, dosing convenience, and individual risk profiles.

Nurodur should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, excessive heat, and direct sunlight to maintain potency throughout the shelf life.

Nurodur is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen gastrointestinal irritation, but patients should follow the specific instructions provided by their prescriber.

Serious risks include gastrointestinal bleeding or ulceration, renal impairment, cardiovascular events such as heart attack or stroke, and severe allergic reactions like anaphylaxis. Patients should seek immediate medical attention if they experience symptoms such as black stools, sudden kidney problems, chest pain, or breathing difficulty.

Nurodur should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, or advanced kidney disease. It is also contraindicated in the third trimester of pregnancy and should be used with caution in elderly patients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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