Nurofen 400 (Ibuprofen)

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which lowers prostaglandin production. This reduction diminishes inflammation, lowers the hypothalamic set‑point for temperature, and decreases the sensitivity of pain receptors.

The appropriate dose of Nurofen 400 is determined by a prescriber based on the individual’s age, weight, and clinical condition. Adults typically receive one tablet as needed, but the exact regimen should follow the healthcare professional’s instructions.

Safety data for ibuprofen in pregnancy are limited, especially in the third trimester, and it is generally avoided. During breastfeeding, ibuprofen passes into milk in small amounts; a healthcare professional should evaluate the risk‑benefit before use.

To order Nurofen 400, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with paracetamol, ibuprofen provides both analgesic and anti‑inflammatory effects, whereas paracetamol is primarily analgesic and antipyretic. Ibuprofen may be preferred when inflammation is a key component, but it carries a higher risk of gastrointestinal and renal side effects.

Store Nurofen 400 tablets at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

Nurofen 400 is taken orally with a full glass of water. It can be taken with or without food; taking it with food may reduce the likelihood of stomach upset.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, and severe allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience vomiting blood, black stools, sudden loss of kidney function, or signs of a severe allergy.

Nurofen 400 should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active peptic ulcer disease, severe renal or hepatic impairment, uncontrolled heart failure, and by pregnant women in the third trimester unless advised by a physician.