Product image of Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Nurofen Cold And Flu

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and Pseudoephedrine Hydrochloride, the active ingredients in Nurofen Cold And Flu, are a nonsteroidal anti‑inflammatory drug and a sympathomimetic decongestant presented as oral tablets for oral use. They are intended to relieve common cold and flu symptoms such as headache, fever, nasal congestion and body aches in adults and children over the appropriate age.

GNH India supplies Nurofen Cold And Flu as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Manufacturer / TM Owner

Reckitt Benckiser D.O.O.

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Indications & Clinical Uses

Nurofen Cold And Flu combines an NSAID and a nasal decongestant to treat symptoms of viral upper respiratory infections.

  • Headache: provides analgesic relief by reducing pain signals.
  • Fever: lowers elevated body temperature through antipyretic action.
  • Nasal congestion: clears blocked nasal passages by shrinking swollen mucosa.
  • Body aches: eases muscular discomfort associated with cold and flu.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin synthesis and thereby producing analgesic and antipyretic effects. Pseudoephedrine Hydrochloride acts as an alpha‑adrenergic agonist, causing vasoconstriction of the nasal mucosal blood vessels, which reduces swelling and improves airway patency. The oral formulation allows systemic absorption of both agents, delivering rapid symptom control.

Side Effects

Common and serious adverse reactions may occur with Nurofen Cold And Flu; they vary in frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Dyspepsia: indigestion or heartburn.
  • Dizziness: transient light‑headedness.
  • Insomnia: difficulty falling or staying asleep.
  • Headache: mild to moderate pain.
  • Elevated blood pressure: slight increase in some users.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Cardiovascular events: chest pain, palpitations, or stroke.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before using Nurofen Cold And Flu, consider the following precautions to ensure safe and effective use.

  • Medical history review: disclose any cardiovascular disease, hypertension, ulcer, kidney or liver disorders.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Concomitant NSAIDs: avoid taking additional NSAIDs to reduce risk of gastrointestinal injury.
  • Alcohol consumption: limit alcohol as it may increase stomach irritation.
  • Age restrictions: not recommended for children under the specified age without medical advice.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Nurofen Cold And Flu may interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • MAO inhibitors: combined use can cause hypertensive crisis due to pseudoephedrine.
  • Anticoagulants (e.g., warfarin): ibuprofen may increase bleeding risk.
  • Other sympathomimetics: additive vasoconstrictive effects may raise blood pressure.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: pseudoephedrine may reduce their effectiveness.
  • SSRIs or SNRIs: increased risk of bleeding when combined with ibuprofen.
  • Lithium: pseudoephedrine can raise lithium serum levels.

Frequently Asked Questions

Nurofen Cold And Flu is an over‑the‑counter combination of ibuprofen and pseudoephedrine designed to relieve common cold and flu symptoms. It helps reduce headache, fever, body aches, and nasal congestion, providing a convenient single product for adults and older children experiencing these viral‑related discomforts.

Ibuprofen works by blocking cyclooxygenase enzymes, which lowers prostaglandin production and reduces pain and fever. Pseudoephedrine acts as an alpha‑adrenergic agonist, tightening blood vessels in the nasal lining, which decreases swelling and opens the airways. Together they target both pain/fever and nasal blockage.

The appropriate dose of Nurofen Cold And Flu is determined by a qualified healthcare professional based on age, weight, and clinical condition. Patients should follow the prescriber’s instructions or the label directions and never exceed the recommended amount.

Pregnant or breastfeeding individuals should consult their doctor before using Nurofen Cold And Flu. Ibuprofen may affect fetal renal function in the third trimester, and pseudoephedrine can reduce uterine blood flow. A healthcare provider can assess risks and suggest safer alternatives if needed.

To place an order, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with a typical paracetamol‑phenylephrine combo, Nurofen Cold And Flu offers the anti‑inflammatory and analgesic benefits of ibuprofen, which can be more effective for muscle aches and fever, while pseudoephedrine provides a stronger decongestant effect than phenylephrine. However, ibuprofen carries a higher risk of gastrointestinal irritation, so individual patient factors guide choice.

Store the tablets at ambient temperature, preferably below 25 °C, in the original blister pack or container. Keep them away from moisture, direct sunlight, and out of reach of children. Do not refrigerate or freeze the product, as this can affect tablet integrity.

Nurofen Cold And Flu is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce stomach upset. Swallow the tablet whole; do not crush, chew, or split unless specifically instructed by a healthcare professional.

Serious risks include allergic reactions such as rash, swelling, or anaphylaxis; gastrointestinal bleeding or ulceration, especially with prolonged use; and cardiovascular events like hypertension, chest pain, or stroke. Users should seek immediate medical attention if they experience any of these severe symptoms.

Individuals with known hypersensitivity to ibuprofen, pseudoephedrine, or any component of the formulation should avoid the product. It is also contraindicated in patients with uncontrolled hypertension, severe coronary artery disease, recent myocardial infarction, active gastric ulcer, or those taking monoamine‑oxidase inhibitors. Children below the approved age limit should not use it without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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