Product image of Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Nurofen Cold And Flu

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and Pseudoephedrine Hydrochloride, the active ingredients in Nurofen Cold And Flu, are a nonsteroidal anti‑inflammatory drug (NSAID) and a sympathomimetic decongestant presented as an oral formulation for oral use. They are intended to relieve common cold and influenza symptoms such as nasal congestion, headache, fever, sore throat and body aches, providing symptomatic relief for adults.

GNH India supplies Nurofen Cold And Flu as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Hellas Healthcare Sa

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Indications & Clinical Uses

  • Nurofen Cold And Flu, containing ibuprofen and pseudoephedrine, is used to alleviate symptoms of the common cold and influenza.
  • Nasal congestion: reduces swelling of nasal mucosa, easing breathing.
  • Headache, fever and body aches: provides analgesic, antipyretic and anti‑inflammatory relief.
  • Sore throat: alleviates pain and inflammation associated with throat irritation.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin synthesis and thereby producing analgesic, antipyretic and anti‑inflammatory effects. Pseudoephedrine hydrochloride acts as an α‑adrenergic agonist, causing vasoconstriction of the nasal mucosal blood vessels, which reduces edema and improves airway patency. The combined actions address both pain/fever and nasal congestion.

Side Effects

The following adverse reactions have been reported with ibuprofen and pseudoephedrine combinations.

Common Side Effects

  • Nausea
  • Dizziness
  • Stomach discomfort

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Severe allergic reaction (anaphylaxis)
  • Elevated blood pressure or hypertensive crisis

Precautions & Warnings

  • When using Nurofen Cold And Flu, consider the following precautions.
  • Cardiovascular disease or hypertension: consult a healthcare professional before use.
  • History of gastric ulcer or bleeding: avoid or use under medical supervision.
  • Asthma or respiratory disorders: pseudoephedrine may exacerbate symptoms.
  • Kidney or liver impairment: dosage adjustment may be required.
  • Do not combine with other NSAIDs or decongestants without advice.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Nurofen Cold And Flu may interact with several medicines; the most important are listed below.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis with pseudoephedrine.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: pseudoephedrine may reduce antihypertensive effect.
  • Diuretics: may enhance electrolyte disturbances.
  • Beta‑blockers: may mask tachycardia caused by pseudoephedrine.

Frequently Asked Questions

Nurofen Cold And Flu is an over‑the‑counter combination of ibuprofen and pseudoephedrine designed to relieve common cold and influenza symptoms. It targets nasal congestion, headache, fever, sore throat and body aches, providing both analgesic/antipyretic and decongestant effects to improve comfort during a viral upper‑respiratory infection.

Ibuprofen belongs to the nonsteroidal anti‑inflammatory drug class. It blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins—compounds that mediate pain, fever and inflammation. By lowering prostaglandin levels, ibuprofen produces analgesic, antipyretic and anti‑inflammatory actions that help ease cold‑related discomfort.

The appropriate dose is set by a healthcare professional based on factors such as the patient’s age, weight, overall health and severity of symptoms. The product label provides general guidance, but individuals should follow the prescriber’s instructions or the directions on the packaging and should not exceed the recommended maximum daily amount.

Safety in pregnancy and lactation has not been fully established. Ibuprofen is generally avoided in the third trimester because of potential fetal risks, and pseudoephedrine may be contraindicated in certain pregnant women due to possible cardiovascular effects. Breastfeeding mothers should consult a healthcare provider before using this product to weigh benefits against potential risks.

To place an order, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After submission, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with formulations that contain only paracetamol and a decongestant, Nurofen Cold And Flu adds ibuprofen, offering stronger anti‑inflammatory and analgesic effects. This can be advantageous for patients with pronounced body aches or fever. However, the ibuprofen component introduces gastrointestinal and cardiovascular considerations that are less prominent with acetaminophen‑based products.

The product should be stored at ambient temperature, ideally below 25 °C. Keep it in the original packaging to protect it from moisture, heat and direct sunlight. Do not store in a refrigerator or freezer, and keep it out of reach of children.

Nurofen Cold And Flu is taken orally. The tablet should be swallowed whole with a full glass of water, preferably with food to reduce stomach irritation. Patients should follow the dosing instructions on the label or those provided by their healthcare professional and avoid crushing or chewing the tablet.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, and hypertensive crises or significant blood‑pressure elevation due to the pseudoephedrine component. Patients experiencing chest pain, severe headache, visual changes, or signs of bleeding should seek immediate medical attention.

Individuals who are allergic to ibuprofen, pseudoephedrine or any other ingredients should avoid the product. It is also contraindicated for children under the age specified on the label, patients with uncontrolled hypertension, severe coronary artery disease, certain heart rhythm disorders, recent myocardial infarction, or those taking monoamine oxidase inhibitors. Consultation with a healthcare professional is essential before use in these groups.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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