Product image of Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Nurofen Cold And Flu

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and pseudoephedrine hydrochloride, the active ingredients in Nurofen Cold and Flu, are a non‑steroidal anti‑inflammatory drug and a nasal decongestant presented as tablets for oral use. They relieve pain, reduce fever, and alleviate nasal congestion associated with colds and flu in adults, offering a combined approach to inflammatory and decongestant therapy.

GNH India supplies Nurofen Cold and Flu as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Hellas Healthcare Sa

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Indications & Clinical Uses

Nurofen Cold and Flu combines an NSAID and a decongestant to address symptoms of upper‑respiratory infections.

  • Common cold: reduces fever, aches and nasal congestion.
  • Influenza: eases body aches, headache and high temperature.
  • Sinusitis: diminishes sinus pressure and nasal blockage.
  • Seasonal allergies with cold symptoms: provides pain relief while opening nasal passages.
  • Flu‑like viral illness: helps control fever and discomfort.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis and thereby reducing inflammation, pain, and fever. Pseudoephedrine hydrochloride acts as a sympathomimetic agonist on α‑adrenergic receptors in nasal mucosal vessels, causing vasoconstriction that lessens edema and improves airway patency.

Side Effects

Common Side Effects

  • Nausea or upset stomach.
  • Heartburn or indigestion.
  • Dizziness or mild headache.
  • Insomnia or restlessness.
  • Mild increase in blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer formation.
  • Severe allergic reactions such as rash, swelling, or anaphylaxis.
  • High blood pressure crises.
  • Cardiac arrhythmias.
  • Liver or kidney function impairment.

Precautions & Warnings

When using Nurofen Cold and Flu, consider the following precautions:

  • Pregnancy: avoid in the third trimester due to potential fetal risks.
  • Cardiovascular disease: use with caution as pseudoephedrine may raise blood pressure.
  • History of gastric ulcer or bleeding: ibuprofen can exacerbate gastrointestinal injury.
  • Renal impairment: monitor kidney function, especially in prolonged use.
  • Asthma: pseudoephedrine may trigger bronchospasm in susceptible individuals.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis with pseudoephedrine.
  • Beta‑blockers: may diminish decongestant effectiveness.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in antihypertensive effect.
  • Corticosteroids: heightened risk of ulcer formation.
  • Alcohol: may increase gastrointestinal irritation.
  • Lithium: pseudoephedrine can raise serum lithium levels.

Frequently Asked Questions

Nurofen Cold and Flu is a combination tablet that provides pain relief, reduces fever, and eases nasal congestion associated with common colds, influenza and related upper‑respiratory symptoms. It is intended for short‑term, over‑the‑counter use in adults.

Ibuprofen belongs to the non‑steroidal anti‑inflammatory drug class. It blocks cyclo‑oxygenase enzymes, lowering prostaglandin production, which reduces inflammation, pain, and fever.

The appropriate dose is determined by a qualified healthcare professional or according to the product label. Patients should follow the prescriber’s instructions or the dosing guidelines printed on the packaging.

Use of this product is generally not recommended in the third trimester of pregnancy because of potential fetal risks. Breastfeeding mothers should consult a healthcare provider before use, as ibuprofen and pseudoephedrine can pass into breast milk.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike single‑ingredient products, Nurofen Cold and Flu combines an NSAID (ibuprofen) with a decongestant (pseudoephedrine), offering simultaneous pain‑relief and nasal decongestion. This dual action can be more convenient than taking separate analgesic and decongestant products.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and keep out of reach of children.

The product is taken orally with a full glass of water. It is usually swallowed whole and not chewed or dissolved, unless the label specifically permits an alternative method.

Serious risks include gastrointestinal bleeding or ulceration from ibuprofen, severe allergic reactions such as anaphylaxis, and significant increases in blood pressure or heart rate caused by pseudoephedrine. Patients should seek immediate medical attention if these events occur.

Individuals with known hypersensitivity to ibuprofen, pseudoephedrine, or any component of the tablet should avoid it. It is also contraindicated in patients with active peptic ulcer disease, uncontrolled hypertension, severe coronary artery disease, or those taking monoamine oxidase inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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