Product image of Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Nurofen Cold And Flu

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Nurofen Cold And Flu (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and Pseudoephedrine Hydrochloride, the active ingredient in Nurofen Cold And Flu, is a nonsteroidal anti‑inflammatory drug and sympathomimetic decongestant presented as an oral formulation for over‑the‑counter use. It provides analgesic, antipyretic and nasal decongestant effects for adults experiencing cold‑related symptoms.

GNH India supplies Nurofen Cold And Flu as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Kft

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Indications & Clinical Uses

Nurofen Cold And Flu combines an NSAID and a decongestant to address common cold‑related complaints.

  • Nasal congestion: reduces swelling of nasal passages and eases breathing.
  • Headache: alleviates pain associated with sinus pressure and tension.
  • Fever: lowers elevated body temperature.
  • Muscle aches and pains: relieves soreness and stiffness caused by viral illness.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase enzymes COX‑1 and COX‑2, decreasing prostaglandin synthesis and thereby providing analgesic, antipyretic and anti‑inflammatory actions. Pseudoephedrine hydrochloride stimulates α‑adrenergic receptors in the nasal mucosa, causing vasoconstriction that reduces mucosal edema and relieves nasal congestion.

Side Effects

Nurofen Cold And Flu may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild stomach upset after oral intake.
  • Dizziness: transient light‑headedness.
  • Insomnia: difficulty falling asleep.
  • Dry mouth: reduced salivation.
  • Increased heart rate: mild tachycardia.
  • Stomach discomfort: mild abdominal pain.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: severe stomach or intestinal bleeding.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Hypertension: significant rise in blood pressure.
  • Arrhythmia: irregular heart rhythm.
  • Liver injury: elevated liver enzymes or hepatitis.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before using Nurofen Cold And Flu, consider the following safety measures.

  • Do not exceed the recommended daily dose: follow prescriber or label instructions.
  • Avoid if you have a history of gastric ulcer or bleeding: NSAIDs can aggravate these conditions.
  • Use with caution in hypertension: pseudoephedrine may raise blood pressure.
  • Pregnant or breastfeeding women should consult a healthcare professional before use.
  • Not for children under the age specified on the label: dosage forms are intended for adults.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Nurofen Cold And Flu can interact with several medicines; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Monoamine oxidase inhibitors (MAOIs): heightened pressor response.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.
  • Lithium: pseudoephedrine may raise lithium levels.

Moderate Interactions (Monitor Closely)

  • Antihypertensives (e.g., ACE inhibitors): possible reduction in blood‑pressure control.
  • Diuretics: may enhance pseudoephedrine‑induced electrolyte changes.
  • Beta‑blockers: may blunt heart‑rate response.
  • Other sympathomimetics: additive stimulant effects.
  • Alcohol: increased gastric irritation and CNS depression.
  • Caffeine: may intensify nervous system stimulation.

Frequently Asked Questions

Nurofen Cold And Flu is an over‑the‑counter oral medication that combines ibuprofen and pseudoephedrine to relieve common cold‑related symptoms such as nasal congestion, headache, fever and muscle aches. It provides both analgesic/antipyretic and decongestant actions in a single product.

Ibuprofen blocks the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which reduces the formation of prostaglandins—compounds that cause pain, fever and inflammation. By lowering prostaglandin levels, ibuprofen eases headache, reduces fever and diminishes muscle soreness.

The appropriate dose is determined by the prescribing healthcare professional or the product label. Patients should follow the specific instructions provided by their doctor or the directions on the packaging and should not exceed the recommended amount.

Pregnant or breastfeeding individuals should consult their physician before using Nurofen Cold And Flu. Ibuprofen is generally avoided in the third trimester, and pseudoephedrine may affect fetal circulation, so professional guidance is essential.

To request supply, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike single‑ingredient formulations, Nurofen Cold And Flu combines an NSAID (ibuprofen) with a decongestant (pseudoephedrine), offering both pain/fever control and nasal decongestion in one dose. This dual action can be more convenient than taking separate analgesic and decongestant products.

Store the tablets at ambient temperature below 25 °C, in their original container, and protect them from moisture and direct sunlight. Do not keep the product in a humid bathroom cabinet or in a freezer.

The medication is taken orally with a full glass of water. It is intended for adult use and should be swallowed whole; do not crush or chew the tablets unless the label specifically permits it.

Serious risks include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, significant increases in blood pressure, and rare cardiac arrhythmias. Patients should seek immediate medical attention if they experience unusual bleeding, rash, swelling, chest pain or rapid heartbeat.

Individuals with a known allergy to ibuprofen, pseudoephedrine or any NSAID, those with active gastric ulcers, uncontrolled hypertension, severe heart disease, or who are taking MAO inhibitors should avoid this product. Children below the age specified on the label should also not use it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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