Product image of Nurofen Dla Dzieci (Ibuprofen) supplied by GNH India

Nurofen Dla Dzieci

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Dla Dzieci (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Dla Dzieci, is a nonsteroidal anti‑inflammatory drug presented as a rectal formulation for rectal use. It provides effective pain relief, reduces fever, and eases inflammation in pediatric patients, helping to manage common childhood ailments such as teething discomfort, minor injuries, and viral fevers.

GNH India supplies Nurofen Dla Dzieci as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Reckitt Benckiser (Poland) S.A.

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve pain, lower fever, and reduce swelling in children.

  • Pain relief in children: reduces mild to moderate pain associated with injuries, teething, or postoperative discomfort.
  • Fever reduction in children: lowers elevated body temperature caused by infections or inflammatory conditions.
  • Inflammation relief in children: decreases swelling and redness in localized inflammatory processes.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and limits vascular permeability, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Stomach upset or dyspepsia
  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions such as anaphylaxis
  • Renal impairment or acute kidney injury
  • Hepatotoxicity
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

When using ibuprofen in children, several precautions should be observed to ensure safety.

  • Dosage adjustment: follow prescriber guidance based on the child’s age and weight.
  • Gastrointestinal risk: monitor for stomach pain, bleeding, or ulcer symptoms.
  • Renal function: avoid use in children with pre‑existing kidney disease or dehydration.
  • Allergy: do not use if the child has known hypersensitivity to ibuprofen or other NSAIDs.
  • Bleeding risk: use cautiously with anticoagulant therapy or bleeding disorders.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct heat.

Avoid Interactions

Ibuprofen can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Concurrent use of other NSAIDs: heightened gastrointestinal toxicity.
  • Corticosteroids: elevated chance of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated children.
  • Diuretics: potential for decreased kidney perfusion.
  • Lithium: ibuprofen can raise lithium serum concentrations, risking toxicity.

Frequently Asked Questions

Nurofen Dla Dzieci is a pediatric formulation of ibuprofen used to relieve mild to moderate pain, lower fever, and reduce inflammation in children. It is commonly employed for conditions such as teething discomfort, minor injuries, postoperative pain, and fever associated with viral or bacterial infections.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish pain signaling, lower the hypothalamic set‑point for body temperature, and decrease vascular permeability, providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Nurofen Dla Dzieci is determined by a qualified healthcare professional based on the child’s age, weight, and clinical condition. Caregivers should follow the prescriber’s instructions and the product label; no specific dosing regimen should be assumed without professional guidance.

Ibuprofen is generally not recommended during the third trimester of pregnancy because it may affect fetal circulation. For breastfeeding mothers, ibuprofen is excreted in small amounts in breast milk, and use should be discussed with a healthcare provider to weigh potential risks and benefits.

To order Nurofen Dla Dzieci, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

The primary alternative for pediatric fever and pain is paracetamol (acetaminophen). While both lower temperature and relieve pain, ibuprofen also has anti‑inflammatory properties. Ibuprofen may be preferred when inflammation is a component, but it carries a higher risk of gastrointestinal and renal side effects compared with paracetamol.

Nurofen Dla Dzieci should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and excessive heat to maintain stability and potency throughout its shelf life.

The product is formulated for rectal administration. The appropriate dose, as prescribed, is inserted into the rectum using the supplied applicator or as directed by a healthcare professional, ensuring the child is positioned comfortably to allow complete delivery of the medication.

Serious risks associated with ibuprofen in children include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, liver toxicity, and rare skin disorders like Stevens‑Johnson syndrome. Caregivers should seek immediate medical attention if any of these symptoms appear.

Children with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and children receiving certain anticoagulant therapies should avoid using Nurofen Dla Dzieci. Consultation with a healthcare provider is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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