Nurofen Duo (Ibuprofen, Paracetamol)

Ibuprofen blocks cyclo‑oxygenase enzymes, lowering prostaglandin production that drives inflammation and pain. Paracetamol works mainly in the central nervous system, inhibiting a COX variant and influencing serotonergic pathways to reduce pain perception and temperature regulation. Together they provide complementary analgesic and antipyretic effects.

The appropriate dose of Nurofen Duo is determined by a qualified prescriber based on the individual’s age, weight, medical history and the severity of symptoms. Healthcare professionals set the dosing schedule and duration according to current clinical guidelines.

Use of ibuprofen‑containing products is generally avoided in the third trimester of pregnancy because of fetal cardiovascular risks, and caution is advised throughout pregnancy. Paracetamol is considered relatively safe when used at recommended doses. Breastfeeding mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

The combination offers additive analgesic and antipyretic effects, often achieving faster pain relief than either component alone. It may reduce the need for higher individual doses, potentially lowering the risk of dose‑related side effects, but it also introduces combined safety considerations such as liver and gastrointestinal monitoring.

Store tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Nurofen Duo is taken orally with a full glass of water. It may be taken with or without food, although taking it with food can reduce the likelihood of gastrointestinal discomfort.

Serious adverse events include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity, renal impairment and anaphylaxis. Patients should seek immediate medical attention if they experience symptoms like vomiting blood, severe rash, jaundice or sudden kidney‑related problems.

Individuals with known hypersensitivity to ibuprofen, other NSAIDs, or paracetamol should avoid the product. It is also contraindicated in patients with active peptic ulcer disease, severe liver or kidney impairment, uncontrolled hypertension, and in the third trimester of pregnancy.