Product image of Nurofen Durance (Ibuprofen) supplied by GNH India

Nurofen Durance

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Durance (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Durance, is a non‑steroidal anti‑inflammatory drug presented as a strength/form for oral use. It treats pain, inflammation and fever in adults and children when appropriate.

GNH India supplies Nurofen Durance as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Hellas Healthcare Sa

1
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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve several common conditions.

  • Headache: reduces pain and associated discomfort.
  • Dental pain: alleviates post‑extraction or procedure soreness.
  • Musculoskeletal pain: eases aches from strains, sprains and minor arthritis.
  • Fever: lowers elevated body temperature.
  • Menstrual cramps: diminishes cramping and pelvic discomfort.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. This reduction in prostaglandin levels dampens the inflammatory response and lowers the body’s pain‑signalling pathways.

Side Effects

Adverse reactions can range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient headache may occur.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated blood pressure: slight increase in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage.
  • Renal impairment: reduced kidney function or acute failure.
  • Severe allergic reaction: anaphylaxis, angioedema or bronchospasm.
  • Liver injury: hepatitis or elevated liver enzymes.
  • Cardiovascular events: increased risk of heart attack or stroke.

Precautions & Warnings

Before using Nurofen Durance, consider the following safety measures.

  • Contraindications: avoid if you have a known allergy to ibuprofen or other NSAIDs.
  • Gastrointestinal risk: use with caution if you have a history of ulcers or bleeding.
  • Cardiovascular caution: patients with heart disease should consult a physician.
  • Renal function: monitor kidney health in those with existing renal impairment.
  • Pregnancy and lactation: discuss risks with a healthcare professional before use.
  • Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture.

Avoid Interactions

Ibuprofen may interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants: increased risk of bleeding when combined with warfarin or other blood thinners.
  • High‑dose aspirin: additive gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: heightened cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce antihypertensive effect and affect kidney function.
  • Diuretics: potential for reduced renal perfusion.
  • Lithium: ibuprofen can increase lithium serum levels.
  • Methotrexate: may raise methotrexate toxicity.
  • SSRIs: combined use can increase bleeding risk.

Frequently Asked Questions

Nurofen Durance contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and menstrual cramps.

Ibuprofen works by blocking the cyclo‑oxygenase (COX) enzymes that produce prostaglandins, which are chemicals that trigger inflammation, pain and fever. Reducing prostaglandin production helps lower these symptoms.

The appropriate dose of Nurofen Durance is determined by a prescriber based on the patient’s age, weight, condition being treated and any other medical considerations. Patients should follow the healthcare professional’s instructions.

Use of ibuprofen during pregnancy, especially in the third trimester, and while breastfeeding should only be done under medical advice. A healthcare professional can assess the benefits and risks for the mother and infant.

To order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Nurofen Durance provides ibuprofen, which has a well‑established efficacy and safety profile comparable to other NSAIDs such as naproxen or diclofenac. Choice of NSAID often depends on individual tolerance, dosing frequency, and specific risk factors.

Store Nurofen Durance tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep out of reach of children.

Nurofen Durance is taken orally, usually with water. It can be taken with or without food, but taking it with food may reduce stomach irritation.

Serious risks include gastrointestinal bleeding or ulceration, kidney injury, severe allergic reactions such as anaphylaxis, and an increased risk of cardiovascular events like heart attack or stroke, especially with long‑term use.

Individuals with a known allergy to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, or advanced kidney disease should avoid Nurofen Durance unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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