Product image of Nurofen Express (Ibuprofen) supplied by GNH India

Nurofen Express

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Express (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Express, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the temporary relief of mild to moderate pain, fever and inflammation in adults and children when used according to label instructions.

GNH India supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements to ensure product integrity.

Manufacturer / TM Owner

Reckitt Benckiser Hellas Healthcare Sa

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Indications & Clinical Uses

Ibuprofen, an NSAID, works by reducing prostaglandin-mediated inflammation and is indicated for several common conditions.

  • Headache: provides relief from tension‑type and mild migraine headaches.
  • Dental pain: reduces discomfort associated with toothaches and post‑extraction soreness.
  • Fever: lowers elevated body temperature caused by infection or other febrile illnesses.
  • Musculoskeletal pain: eases aches from minor sprains, strains or arthritis flare‑ups.

How It Works

  • Ibuprofen inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which convert arachidonic acid into prostaglandins. By blocking prostaglandin synthesis, it diminishes inflammation, pain signalling, and fever generation at sites of tissue injury while maintaining most normal platelet function through reversible inhibition.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient headache unrelated to the condition being treated.
  • Dizziness: occasional light‑headedness or vertigo.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: severe stomach or intestinal bleeding.
  • Renal impairment: reduced kidney function or acute renal failure.
  • Severe allergic reactions: anaphylaxis, angioedema or Stevens‑Johnson syndrome.

Precautions & Warnings

When using ibuprofen tablets, consider the following precautions to minimize risk.

  • Assess medical history: evaluate for existing gastrointestinal ulcers, bleeding disorders or cardiovascular disease.
  • Use lowest effective dose: limit duration and dose to the minimum needed for symptom control.
  • Avoid in late pregnancy: contraindicated during the third trimester due to fetal risks.
  • Monitor renal function: patients with kidney disease should be observed for changes in creatinine.
  • Caution with other NSAIDs: concurrent use may increase adverse effect risk.
  • Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with other medicines, altering their effectiveness or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding potential.
  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair kidney function.
  • Lithium: ibuprofen can raise lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in diuretic efficacy and renal perfusion.
  • Methotrexate: decreased clearance leading to toxicity.
  • Corticosteroids: additive risk of gastrointestinal ulceration.
  • Antihypertensives (beta‑blockers): may blunt blood pressure control.
  • Oral hypoglycemics: potential alteration of blood glucose levels.

Frequently Asked Questions

Nurofen Express contains ibuprofen and is used for the temporary relief of mild to moderate pain, reduction of fever, and alleviation of inflammation associated with conditions such as headaches, dental discomfort, musculoskeletal aches, and febrile illnesses.

Ibuprofen blocks the cyclooxygenase enzymes COX‑1 and COX‑2, preventing the conversion of arachidonic acid into prostaglandins. This reduction in prostaglandin production lowers inflammation, diminishes pain signals, and helps bring down elevated body temperature.

The appropriate dose of Nurofen Express is determined by a healthcare professional based on the individual’s age, weight, and clinical need. Over‑the‑counter labeling typically provides general dosing ranges, but the prescriber’s guidance should always be followed.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal risks. During the first and second trimesters, it should only be used if clearly needed and after consulting a physician. Limited data are available for breastfeeding, so a healthcare provider should assess the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Nurofen Express (ibuprofen) offers combined analgesic, antipyretic and anti‑inflammatory activity, whereas paracetamol provides mainly analgesic and antipyretic effects without significant anti‑inflammatory action. Compared with other NSAIDs, ibuprofen has a relatively favorable safety profile for short‑term use but shares class‑related gastrointestinal and renal cautions.

Store Nurofen Express tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Nurofen Express tablets are taken by mouth with a full glass of water. They may be taken with or without food, although taking them with food can reduce the likelihood of gastrointestinal discomfort. Follow the dosing instructions provided by the prescriber or the product label.

Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, and rare but life‑threatening allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice black stools, unexplained bruising, sudden swelling, or difficulty breathing.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or advanced kidney disease should avoid Nurofen Express. It is also contraindicated in the third trimester of pregnancy and in patients taking certain anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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