Product image of Nurofen Express (Ibuprofen Sodium) supplied by GNH India

Nurofen Express

Active Ingredient:
Ibuprofen Sodium
Origin:
EU

Nurofen Express (Ibuprofen Sodium)

Ibuprofen, the active ingredient in Nurofen Express, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a solid oral dosage form for short‑term, over‑the‑counter pain relief use. It helps reduce fever, alleviate mild to moderate pain and lessen inflammation in adults and children when used as directed.

GNH India supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Hellas Healthcare Sa

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Indications & Clinical Uses

Nurofen Express, an ibuprofen‑based NSAID, acts on inflammatory pathways to provide symptomatic relief in several common conditions.

  • Headache: eases tension‑type and mild migraine symptoms.
  • Dental pain: reduces discomfort after dental procedures or toothache.
  • Musculoskeletal pain: alleviates aches from strains, sprains and minor joint inflammation.
  • Fever: lowers elevated body temperature in febrile adults and children.
  • Menstrual cramps: lessens dysmenorrhoeic pain associated with menstrual cycles.

How It Works

  • Ibuprofen sodium inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate pain, fever and inflammation. By reducing prostaglandin levels at sites of tissue injury, it provides analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Adverse reactions to ibuprofen sodium may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient headache may occur.
  • Dizziness: light‑headed feeling or vertigo.
  • Skin rash: mild erythema or itching.
  • Elevated blood pressure: slight increase in systolic/diastolic readings.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe allergic reaction: anaphylaxis, angio‑edema.
  • Hepatic injury: elevated liver enzymes or hepatitis.
  • Renal impairment: acute kidney injury or reduced urine output.
  • Cardiovascular events: myocardial infarction or stroke.

Precautions & Warnings

When using Nurofen Express, consider the following safety measures:

  • Assess contraindications: avoid if known allergy to ibuprofen or other NSAIDs.
  • Monitor gastrointestinal health: patients with ulcer history should use caution.
  • Evaluate renal function: adjust use in those with chronic kidney disease.
  • Review cardiovascular risk: use the lowest effective dose for the shortest duration.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture.

Avoid Interactions

Ibuprofen sodium can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants: increased risk of bleeding with warfarin or direct oral anticoagulants.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors/ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Diuretics: potential for decreased effectiveness and electrolyte imbalance.
  • Lithium: ibuprofen may raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Nurofen Express contains ibuprofen sodium, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and menstrual cramps.

Ibuprofen sodium works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which reduces the production of prostaglandins—chemical messengers that cause pain, fever and inflammation at the site of tissue injury.

The appropriate dose of Nurofen Express is determined by a prescriber based on the patient’s age, weight, clinical condition and local labeling requirements. Patients should follow the specific instructions provided on the product label or by their healthcare professional.

Ibuprofen sodium should be used with caution during pregnancy, especially in the third trimester, and only if the potential benefit outweighs the risk. Breastfeeding mothers should consult a healthcare professional, as ibuprofen can pass into breast milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nurofen Express delivers ibuprofen sodium, which provides rapid onset of analgesic and antipyretic effects compared with some slower‑acting NSAIDs like naproxen. Its safety profile is similar to other ibuprofen products, but individual tolerability and specific contraindications may differ.

Store Nurofen Express at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date.

Nurofen Express is taken orally, usually with a glass of water. It may be taken with or without food, but patients who experience stomach upset should consider taking it with a meal or an antacid, as advised by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and increased cardiovascular events like heart attack or stroke, particularly with high‑dose or prolonged use.

Individuals with a known allergy to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, advanced kidney disease, or who are in the third trimester of pregnancy should avoid using Nurofen Express unless directed by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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