Product image of Nurofen Express (Ibuprofen Sodium) supplied by GNH India

Nurofen Express

Active Ingredient:
Ibuprofen Sodium
Origin:
EU

Nurofen Express (Ibuprofen Sodium)

Ibuprofen sodium, the active ingredient in Nurofen Express, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of common pains such as headache, toothache, menstrual discomfort and musculoskeletal aches.

GNH India supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide and adheres to stringent quality standards and provides reliable sourcing for healthcare providers across multiple regions.

Manufacturer / TM Owner

Reckitt Benckiser Ireland Ltd.

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Indications & Clinical Uses

Ibuprofen sodium is an NSAID that reduces pain and inflammation by inhibiting prostaglandin synthesis.

  • Headache: alleviates pain and associated discomfort.
  • Toothache: eases dental pain.
  • Menstrual pain: lessens cramps and discomfort.
  • Musculoskeletal pain: reduces joint and muscle aches.
  • Fever: lowers elevated body temperature.

How It Works

  • Ibuprofen sodium works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are key in converting arachidonic acid to prostaglandins. By decreasing prostaglandin production, it reduces peripheral sensitisation of nociceptors, lowers inflammation, and diminishes fever generation in the hypothalamus. This inhibition is dose‑dependent and occurs throughout the body, providing systemic analgesic and antipyretic effects while also limiting the inflammatory response in tissues.

Side Effects

Ibuprofen sodium may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient headache.
  • Dizziness: light‑headed feeling.
  • Skin reactions: mild rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

When using ibuprofen sodium, consider the following precautions to minimise risk.

  • Assess renal function: avoid use in patients with severe kidney disease.
  • Evaluate cardiovascular risk: use cautiously in individuals with hypertension or heart disease.
  • Monitor gastrointestinal health: avoid in those with active ulcers or history of bleeding.
  • Use the lowest effective dose: limit duration to the shortest period needed for symptom relief.
  • Avoid use in late pregnancy: contraindicated in the third trimester.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture.

Avoid Interactions

Ibuprofen sodium can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion.
  • Diuretics: potential for reduced kidney function.
  • Lithium: ibuprofen can increase lithium levels.

Frequently Asked Questions

Nurofen Express contains ibuprofen sodium, an NSAID that is used to relieve mild to moderate pain such as headache, toothache, menstrual cramps, musculoskeletal aches and to reduce fever. It is available without a prescription in many European markets.

Ibuprofen sodium works by reversibly blocking the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for producing prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signalling, and help the body regulate temperature, providing analgesic, anti‑inflammatory and antipyretic effects.

The appropriate dose of Nurofen Express is determined by a qualified prescriber or according to the product label. Dosage depends on the individual’s age, weight, the severity of symptoms and any relevant medical conditions. Always follow the specific instructions provided.

Ibuprofen sodium is generally avoided in the third trimester of pregnancy because of potential risks to the fetus. Use during early pregnancy or while breastfeeding should only be considered after consulting a healthcare professional, who can weigh the benefits against possible risks.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nurofen Express delivers ibuprofen sodium, which is rapidly absorbed and provides effective pain relief comparable to other ibuprofen formulations. Compared with aspirin or naproxen, ibuprofen often has a slightly lower risk of gastrointestinal irritation at standard doses, but individual response can vary.

Store Nurofen Express at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Nurofen Express is taken orally with a glass of water. It can be taken with or without food, although taking it with food may reduce mild stomach discomfort. Swallow the tablet whole; do not crush or chew unless the product label specifically permits it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and kidney injury, especially in patients with pre‑existing renal impairment or when used at high doses for prolonged periods. Prompt medical attention is required if any of these symptoms occur.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or in the third trimester of pregnancy should avoid Nurofen Express. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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