Product image of Nurofen Express (Ibuprofen Sodium Dihydrate) supplied by GNH India

Nurofen Express

Active Ingredient:
Ibuprofen Sodium Dihydrate
Origin:
EU

Nurofen Express (Ibuprofen Sodium Dihydrate)

Ibuprofen, the active ingredient in Nurofen Express, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for common pains such as headache, toothache, menstrual discomfort, musculoskeletal aches and fever.
GNH India supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Poland) S.A.

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Indications & Clinical Uses

Nurofen Express, an NSAID, acts on inflammatory pathways to relieve pain and fever.

  • Headache: reduces pain intensity and associated discomfort.
  • Toothache: alleviates dental pain and inflammation.
  • Menstrual pain: eases cramps and lowers uterine discomfort.
  • Musculoskeletal pain: mitigates aches from strains, sprains or arthritis.
  • Fever: lowers elevated body temperature in acute febrile states.

How It Works

  • Ibuprofen sodium dihydrate reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitisation, inflammation, pain signalling and the hypothalamic set‑point for temperature regulation.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Stomach upset or dyspepsia.
  • Nausea or mild vomiting.
  • Dizziness or light‑headedness.
  • Headache.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis.
  • Liver enzyme elevations or hepatitis.
  • Acute kidney injury.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before using Nurofen Express, consider the following safety measures.

  • Assess medical history: check for ulcers, heart disease, kidney impairment, asthma or bleeding disorders.
  • Avoid concurrent NSAIDs: using multiple NSAIDs increases gastrointestinal and renal risk.
  • Limit alcohol intake: alcohol can exacerbate stomach irritation and bleeding.
  • Use the lowest effective dose for the shortest duration needed.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen may interact with several medicines; monitor accordingly.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulcer formation.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function.
  • Diuretics: may enhance renal effects of ibuprofen.
  • SSRIs: potential for increased bleeding tendency.

Frequently Asked Questions

Nurofen Express contains ibuprofen and is used to temporarily relieve mild to moderate pain such as headache, toothache, menstrual cramps, musculoskeletal aches, and to reduce fever. It is an over‑the‑counter option for short‑term symptom management in adults and children when appropriate.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces inflammation, pain signalling, and the hypothalamic set‑point that controls body temperature, providing analgesic, antipyretic and anti‑inflammatory effects.

The exact dose of Nurofen Express is determined by a healthcare professional or according to the product label. For over‑the‑counter use, adults typically take the recommended amount every 4‑6 hours, not exceeding the maximum daily limit, but the prescriber or label should be consulted for precise guidance.

Safety data for ibuprofen in pregnancy are limited, especially in the third trimester, and it may affect fetal development. Breastfeeding mothers should also exercise caution as ibuprofen can pass into milk. Consultation with a physician or obstetrician is essential before use in these situations.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The most common alternative for similar indications is paracetamol (acetaminophen). While both relieve pain and fever, ibuprofen additionally provides anti‑inflammatory action. Ibuprofen may be more effective for inflammatory pain, but it carries a higher risk of gastrointestinal and renal side effects compared with paracetamol.

Store Nurofen Express at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Nurofen Express is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush or chew unless the product label specifically permits it.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, liver injury, acute kidney damage, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of bleeding, rash, swelling, or sudden loss of kidney function.

People with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, significant kidney or liver disease, or those in the third trimester of pregnancy should avoid Nurofen Express. A healthcare professional should evaluate suitability for all other individuals.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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