Product image of Nurofen Express (Ibuprofen Sodium Dihydrate) supplied by GNH India

Nurofen Express

Active Ingredient:
Ibuprofen Sodium Dihydrate
Origin:
EU

Nurofen Express (Ibuprofen Sodium Dihydrate)

Ibuprofen Sodium Dihydrate, the active ingredient in Nurofen Express, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It reduces pain, fever and inflammation in adults and children when prescribed appropriately.

GNH India supplies Nurofen Express as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Ireland Ltd.

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Indications & Clinical Uses

Ibuprofen, an NSAID, acts on inflammatory pathways to relieve a range of common painful conditions.

  • Headache: provides rapid relief of tension‑type and mild migraine headaches.
  • Dental pain: reduces postoperative discomfort after dental procedures.
  • Musculoskeletal pain: eases aches from sprains, strains and minor joint inflammation.
  • Menstrual pain: alleviates dysmenorrhoea associated with menstrual cramps.
  • Fever: lowers elevated body temperature in acute febrile states.

How It Works

  • Ibuprofen sodium dihydrate inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. By reducing prostaglandin levels at sites of tissue injury, it diminishes peripheral sensitisation of nociceptors and lowers the hypothalamic set‑point for temperature regulation.

Side Effects

Common Side Effects

  • Nausea: mild stomach upset may occur after ingestion.
  • Dyspepsia: occasional indigestion or heartburn.
  • Headache: transient headache in some users.
  • Dizziness: brief sensation of light‑headedness.
  • Diarrhoea: loose stools may be experienced.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or bleeding in the stomach or intestines.
  • Renal impairment: reduced kidney function, especially with prolonged use.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare but serious skin reaction.

Precautions & Warnings

Before using Nurofen Express, consider the following precautions:

  • Contraindications: avoid if you have a known hypersensitivity to ibuprofen or other NSAIDs.
  • Gastro‑intestinal risk: use with food or antacids if you have a history of ulcers or GI bleeding.
  • Cardiovascular caution: limit use in patients with established heart disease or hypertension.
  • Renal function: monitor kidney health in individuals with chronic kidney disease.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding.
  • Store at ambient temperature: keep below 25°C, in the original pack, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.
  • ACE inhibitors or ARBs: may reduce renal perfusion.
  • Lithium: ibuprofen can raise lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible reduction in blood pressure control.
  • Diuretics: may affect renal function.
  • Methotrexate: potential for increased toxicity.
  • SSRIs: modest increase in bleeding risk.
  • Alcohol: enhances gastrointestinal irritation.

Frequently Asked Questions

Nurofen Express contains ibuprofen sodium dihydrate, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, menstrual cramps, and febrile illnesses.

Ibuprofen blocks the activity of cyclo‑oxygenase enzymes (COX‑1 and COX‑2), which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces the signals that cause pain, fever, and inflammation at the site of tissue injury.

The appropriate dose of Nurofen Express is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and overall health status. Always follow the healthcare professional’s instructions and the product label.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, and only if clearly needed. Breastfeeding mothers should consult a healthcare professional, as ibuprofen can pass into breast milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nurofen Express delivers ibuprofen, which offers a balanced profile of analgesic, antipyretic and anti‑inflammatory effects. Compared with aspirin, it has a lower risk of gastric irritation, and unlike selective COX‑2 inhibitors, it provides broader anti‑inflammatory activity but shares similar cardiovascular cautions.

Store Nurofen Express tablets at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Nurofen Express is taken orally with a full glass of water. It can be swallowed with or without food, although taking it with meals may reduce the likelihood of gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and an increased chance of cardiovascular events like heart attack or stroke, particularly with high‑dose or prolonged use.

Individuals with a known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant kidney disease should avoid using Nurofen Express unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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