Product image of Nurofen Extra Strength (Ibuprofen) supplied by GNH India

Nurofen Extra Strength

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Extra Strength (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Extra Strength, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a 400 mg film‑coated tablet for oral use. It treats mild to moderate pain such as headache, dental, muscular and menstrual pain, reduces fever, and helps with minor inflammatory conditions in adults.

GNH India supplies Nurofen Extra Strength as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare (Uk) Ltd

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Indications & Clinical Uses

Ibuprofen, an NSAID, provides analgesic, antipyretic, and anti‑inflammatory effects for several common conditions.

  • Headache: relief of pain and associated discomfort.
  • Dental pain: alleviation of postoperative or toothache discomfort.
  • Muscular pain: reduction of soreness and inflammation in muscles.
  • Menstrual pain: mitigation of dysmenorrhea symptoms.
  • Fever: lowering elevated body temperature.
  • Minor musculoskeletal injuries: decreasing pain and swelling.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, reducing the conversion of arachidonic acid to prostaglandins. This decrease in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may occur with ibuprofen use.

Common Side Effects

  • Stomach discomfort or heartburn
  • Nausea or vomiting
  • Dizziness or light‑headedness
  • Headache

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reaction (anaphylaxis, skin rash)
  • Liver enzyme elevation or hepatitis
  • Kidney function impairment or failure

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess medical history: check for ulcers, heart disease, kidney or liver disease.
  • Avoid use with other NSAIDs: do not combine with aspirin or other ibuprofen products.
  • Limit alcohol consumption: reduces risk of stomach bleeding.
  • Use lowest effective dose: follow prescriber guidance.
  • Store at ambient temperature: keep below 25 °C, in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors (e.g., celecoxib): additive gastrointestinal toxicity.
  • High‑dose aspirin: heightened ulcer risk.
  • Lithium: ibuprofen may raise lithium levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: increased risk of kidney impairment.
  • Methotrexate: ibuprofen can increase toxicity.

Frequently Asked Questions

Nurofen Extra Strength contains ibuprofen, an NSAID that is used to relieve mild to moderate pain such as headache, dental, muscular and menstrual pain, to reduce fever, and to alleviate minor inflammatory conditions like sprains or strains.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are needed to produce prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signals, and lower fever.

The appropriate dose of Nurofen Extra Strength is determined by a prescriber or pharmacist based on the individual's age, weight, medical condition, and response to therapy. Patients should follow the specific instructions provided on the label or by their healthcare professional.

Safety of ibuprofen in pregnancy or while breastfeeding is not fully established. It is generally advised to avoid NSAIDs during the third trimester of pregnancy and to discuss use with a healthcare professional before taking it while pregnant or nursing.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with acetaminophen, ibuprofen offers both analgesic and anti‑inflammatory effects, making it useful for conditions involving inflammation. Unlike stronger prescription NSAIDs, Nurofen Extra Strength is available over the counter and is limited to a 400 mg dose per tablet.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and ensure the container is tightly closed to maintain product stability.

Nurofen Extra Strength is taken orally with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush or chew it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, liver injury, kidney impairment, and increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant kidney or liver disease should avoid using Nurofen Extra Strength unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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