Product image of Nurofen Fastine Liquid Caps (Ibuprofen) supplied by GNH India

Nurofen Fastine Liquid Caps

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Fastine Liquid Caps (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Fastine Liquid Caps, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a softgel capsule for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of mild to moderate pain, fever and inflammation in adults and children when appropriate.

GNH India supplies Nurofen Fastine Liquid Caps as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across all markets, and reliable delivery to meet patient needs.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare B.V.

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Indications & Clinical Uses

Ibuprofen, an NSAID, reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.

  • Pain: Provides relief of mild to moderate acute pain such as headache, dental pain and muscular aches.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: Decreases swelling and discomfort in conditions like arthritis or minor injuries.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This blockade reduces the conversion of arachidonic acid to prostaglandins and thromboxanes, mediators that promote pain, fever and inflammation. The decreased prostaglandin levels in peripheral tissues and the central nervous system underlie its analgesic, antipyretic and anti‑inflammatory actions. By limiting prostaglandin synthesis, ibuprofen also diminishes sensitization of nociceptors and the febrile response in the hypothalamus.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient feeling of light‑headedness.
  • Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.
  • Anaphylaxis or severe allergic reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

When using ibuprofen, consider the following precautions to minimize risk.

  • Assess renal function: avoid use in patients with severe renal impairment.
  • Monitor gastrointestinal health: use the lowest effective dose to reduce ulcer risk.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Limit use in cardiovascular disease: NSAIDs may increase risk of thrombotic events.
  • Store at ambient temperature: keep below 25°C, in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal and GI adverse effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: risk of electrolyte imbalance and renal impairment.
  • Lithium: ibuprofen can increase lithium serum levels.

Frequently Asked Questions

Nurofen Fastine Liquid Caps contain ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and minor arthritic symptoms.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid into prostaglandins. Lower prostaglandin levels reduce the sensations of pain, lower body temperature, and diminish inflammatory swelling.

The appropriate dose of Nurofen Fastine Liquid Caps is determined by a qualified prescriber based on the patient’s age, weight, medical condition, and response to therapy. Healthcare professionals follow local guidelines to select the strength and frequency that best address the individual’s needs.

Ibuprofen is generally avoided during the third trimester of pregnancy because of potential effects on fetal circulation and labor. While short‑term use earlier in pregnancy may be considered, it should only be done under medical supervision. Breastfeeding mothers should consult a healthcare provider, as ibuprofen does pass into milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any required temperature control) and assistance with import documentation.

Nurofen Fastine Liquid Caps deliver ibuprofen, which has a relatively rapid onset and a well‑established safety profile. Compared with naproxen, ibuprofen generally has a shorter half‑life, requiring more frequent dosing, but it may cause less gastrointestinal irritation in some patients. Choice of NSAID depends on individual risk factors and therapeutic goals.

Store the softgel capsules at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light. Do not store in the bathroom or near a heat source, and keep the product out of reach of children.

The capsules are intended for oral administration. Swallow the softgel whole with a full glass of water; do not crush, chew, or open the capsule, as this may affect the intended release profile and increase the risk of gastrointestinal irritation.

Serious risks include gastrointestinal bleeding or ulcer perforation, especially with high‑dose or prolonged use; renal impairment that can lead to acute kidney injury; severe allergic reactions such as anaphylaxis; and cardiovascular events like heart attack or stroke in patients with existing risk factors.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic disease, uncontrolled hypertension, or a history of cardiovascular thrombotic events should avoid using this product unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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