Nurofen Fastine Zavance (Ibuprofen)

Ibuprofen works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which reduces the production of prostaglandins—chemical messengers that promote pain, fever and inflammation. Lower prostaglandin levels result in decreased peripheral pain signalling and a reset of the hypothalamic temperature set‑point.

The appropriate dose of Nurofen Fastine Zavance is determined by a qualified prescriber based on the patient’s age, weight, clinical condition and any concomitant therapies. Patients should follow the prescribing information provided by their healthcare professional.

Ibuprofen should be avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. It may be used earlier in pregnancy only if clearly needed and prescribed. During breastfeeding, ibuprofen passes into milk in small amounts and is generally considered compatible, but a healthcare professional should evaluate the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Ibuprofen, the active ingredient in Nurofen Fastine Zavance, offers a balanced efficacy‑safety profile compared with other NSAIDs such as naproxen or diclofenac. It provides rapid pain relief and antipyretic action with a relatively short half‑life, which may reduce the risk of prolonged gastrointestinal exposure, though individual tolerability varies.

Store Nurofen Fastine Zavance at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain its stability and potency.

Nurofen Fastine Zavance is taken orally, usually with a glass of water. It may be taken with or without food, although taking it with food can help minimise gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased cardiovascular events like heart attack or stroke, particularly with high‑dose or long‑term use.

Ibuprofen is contraindicated in individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, patients in the third trimester of pregnancy, and people with severe heart failure or uncontrolled hypertension unless specifically directed by a physician.