Product image of Nurofen Flextin (Ibuprofen Sodium Dihydrate) supplied by GNH India

Nurofen Flextin

Active Ingredient:
Ibuprofen Sodium Dihydrate
Origin:
EU

Nurofen Flextin (Ibuprofen Sodium Dihydrate)

Ibuprofen, the active ingredient in Nurofen Flextin, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for systemic use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.
GNH India supplies Nurofen Flextin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare B.V.

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Indications & Clinical Uses

Ibuprofen acts on the cyclooxygenase pathway to provide analgesic, antipyretic and anti‑inflammatory effects.

  • Pain: alleviates mild to moderate acute pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infection or inflammatory conditions.
  • Inflammation: reduces swelling and stiffness in conditions like sprains, strains or minor arthritic flare‑ups.

How It Works

  • Ibuprofen sodium dihydrate reversibly inhibits both COX‑1 and COX‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and the hypothalamic set‑point for body temperature, providing analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Adverse reactions may range from mild to serious, depending on individual susceptibility and exposure.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Heartburn: burning sensation in the chest or throat.
  • Dyspepsia: general indigestion or abdominal discomfort.
  • Dizziness: transient light‑headed feeling.
  • Headache: mild to moderate head pain.
  • Diarrhoea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Liver injury: jaundice or elevated liver enzymes.
  • Kidney impairment: reduced urine output or swelling.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Blood disorders: unexplained bruising or low platelet count.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Medical history review: assess for ulcer disease, heart failure, or renal impairment.
  • Lowest effective dose: use the smallest amount needed for symptom control.
  • Allergy check: avoid if known hypersensitivity to NSAIDs or aspirin.
  • Gastro‑intestinal monitoring: watch for signs of bleeding or ulceration.
  • Food intake: take with meals or milk to lessen stomach irritation.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may worsen fluid loss and kidney effects.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Frequently Asked Questions

Nurofen Flextin contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation caused by conditions such as headaches, dental pain, muscle strains, or minor arthritic episodes.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are needed to produce prostaglandins. By lowering prostaglandin levels, it diminishes pain signals, reduces fever, and limits inflammatory swelling.

The appropriate dose of ibuprofen is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and any other medications being taken. Always follow the healthcare professional’s instructions.

Ibuprofen is generally not recommended during the third trimester of pregnancy because it may affect fetal circulation. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen offers a balanced profile of analgesic, antipyretic and anti‑inflammatory activity with a relatively short half‑life, allowing flexible dosing. Compared with stronger NSAIDs like diclofenac, ibuprofen generally has a lower risk of cardiovascular events but similar gastrointestinal cautions.

Store the product at room temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Nurofen Flextin is taken orally, usually with a glass of water. It can be swallowed with or without food, although taking it with meals may reduce stomach irritation.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and an increased chance of heart attack or stroke, especially with high‑dose or prolonged use.

People with a known allergy to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant kidney or liver disease should avoid using ibuprofen unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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