Product image of Nurofen For Children (Ibuprofen) supplied by GNH India

Nurofen For Children

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen For Children (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen For Children, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral suspension for pediatric use. It is formulated for oral administration and is intended to relieve pain, reduce fever, and lessen inflammation in children.

GNH India supplies Nurofen For Children as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Healthcare) Uk Ltd

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Indications & Clinical Uses

Ibuprofen acts as an analgesic and antipyretic by inhibiting prostaglandin synthesis in the inflammatory pathway.

  • Pain relief: alleviates mild to moderate pain such as headache, toothache, or musculoskeletal discomfort in children.
  • Fever reduction: lowers elevated body temperature associated with common infections.
  • Inflammation: reduces swelling and discomfort from minor injuries or inflammatory conditions.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin levels diminishes inflammation, pain signaling, and the hypothalamic set‑point for body temperature, providing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient mild headache.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin erythema or itching.
  • Elevated liver enzymes: transient laboratory changes.

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding or ulceration.
  • Anaphylaxis: acute allergic reaction with airway compromise.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Renal impairment: acute kidney injury, especially with dehydration.
  • Hepatotoxicity: significant liver injury in rare cases.

Precautions & Warnings

When using ibuprofen in children, consider the following safety measures.

  • Age restriction: only for children as directed by a healthcare professional.
  • Existing conditions: avoid if the child has known peptic ulcer disease, severe renal or hepatic impairment.
  • Concomitant NSAIDs: do not combine with other NSAIDs or aspirin to reduce bleeding risk.
  • Allergies: discontinue if signs of hypersensitivity such as rash, swelling, or breathing difficulty appear.
  • Storage: Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose corticosteroids: heightened gastrointestinal ulcer risk.
  • Selective serotonin reuptake inhibitors (SSRIs): potential for bleeding complications.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated patients.
  • Diuretics: possible decrease in renal perfusion.
  • Lithium: ibuprofen can raise lithium serum levels, requiring monitoring.

Frequently Asked Questions

Nurofen For Children contains ibuprofen, an NSAID that provides relief from mild to moderate pain, lowers fever, and reduces inflammation in pediatric patients. It is commonly used for headaches, toothaches, muscle aches, and fever associated with common infections.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels decrease inflammation, diminish pain signals, and reset the hypothalamic temperature set‑point, resulting in antipyretic and analgesic effects.

The appropriate dose of Nurofen For Children is determined by a qualified prescriber or pharmacist based on the child’s age, weight, and clinical condition. Caregivers should follow the specific dosing instructions provided on the product label or by the healthcare professional.

Ibuprofen is generally not recommended during the third trimester of pregnancy and should be used with caution in early pregnancy. While limited data exist for breastfeeding, ibuprofen is excreted in low amounts in breast milk; however, consultation with a healthcare provider is advised before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

The main alternative for pediatric fever reduction is paracetamol (acetaminophen). Ibuprofen, the active ingredient in Nurofen For Children, offers both analgesic and anti‑inflammatory benefits, whereas paracetamol primarily provides analgesic and antipyretic effects without significant anti‑inflammatory activity. Choice depends on clinical needs and safety considerations.

Store Nurofen For Children below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Ensure the container is tightly closed after each use to maintain product stability and potency.

Nurofen For Children is administered orally as a measured dose using the supplied dosing device (e.g., oral syringe or calibrated spoon). The suspension should be shaken gently before each use to ensure uniform distribution of the active ingredient.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and rare but serious skin reactions like Stevens‑Johnson syndrome. Renal impairment and hepatotoxicity can also occur, particularly in children with pre‑existing kidney or liver disease.

Children with known hypersensitivity to ibuprofen or any other NSAID, those with active peptic ulcer disease, severe renal or hepatic impairment, or a history of serious allergic reactions to NSAIDs should avoid using Nurofen For Children. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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