Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug presented as a 200 mg tablet for oral use. It relieves pain, reduces fever and eases inflammation in adults and children when recommended by a healthcare professional.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare France

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Indications & Clinical Uses

Nurofen is an NSAID that acts on inflammatory pathways to provide symptomatic relief in several common conditions.

  • Headache: alleviates pain and reduces associated discomfort.
  • Dental pain: eases postoperative or acute toothache.
  • Musculoskeletal pain: diminishes aches from strains, sprains and minor arthritis.
  • Fever: lowers elevated body temperature in febrile states.
  • Menstrual cramps: reduces uterine cramping and associated pain.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis lessens inflammation, pain signalling and fever generation, providing symptomatic relief across a range of acute and chronic inflammatory conditions.

Side Effects

Adverse reactions to ibuprofen may vary in frequency and severity.

Common Side Effects

  • Gastro‑intestinal upset: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient headache unrelated to the condition being treated.
  • Dizziness: occasional light‑headedness or vertigo.
  • Rash: mild skin redness or itching.
  • Elevated blood pressure: modest rise in systolic or diastolic values.

Serious or Rare Side Effects

  • Gastro‑intestinal bleeding or ulceration.
  • Severe allergic reactions: anaphylaxis, angioedema or bronchospasm.
  • Hepatic injury: marked elevation of liver enzymes or hepatitis.
  • Renal impairment: acute kidney injury or worsening chronic kidney disease.
  • Cardiovascular events: increased risk of myocardial infarction or stroke.

Precautions & Warnings

When using Nurofen, consider the following safety measures:

  • Assess renal function: avoid use in patients with severe kidney impairment.
  • Evaluate gastrointestinal risk: use with caution in those with a history of ulcers or bleeding.
  • Monitor blood pressure: check regularly in hypertensive individuals.
  • Pregnancy and lactation: limit use to the lowest effective dose and only when clearly needed.
  • Drug interactions: review concomitant medications for potential NSAID interactions.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines. Careful management reduces the risk of adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk.
  • Lithium: ibuprofen may raise serum lithium concentrations.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: potential for decreased effectiveness and electrolyte imbalance.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Nurofen contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever and ease inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, fever and menstrual cramps.

Ibuprofen works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which reduces the formation of prostaglandins—compounds that promote inflammation, pain signalling and fever. Lower prostaglandin levels result in decreased discomfort and temperature.

The appropriate dose of Nurofen is determined by a prescriber based on the patient’s age, weight, condition and overall health. Healthcare professionals set the exact amount and dosing interval according to clinical guidelines.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal risks, and it should be used only when clearly needed in earlier trimesters. While small amounts pass into breast milk, it is usually considered compatible with breastfeeding if the lowest effective dose is used.

To place an order, submit an enquiry on the Nurofen product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nurofen (ibuprofen) offers a balanced profile of analgesic, antipyretic and anti‑inflammatory effects, with a relatively short half‑life that allows flexible dosing. Compared with aspirin, it has a lower risk of gastric irritation, and versus naproxen it provides a quicker onset of pain relief but may require more frequent dosing.

Store Nurofen tablets at ambient temperature, ideally below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use after the expiration date.

Nurofen is supplied as oral tablets that are swallowed whole with water. It is intended for oral use only; tablets should not be crushed, chewed or dissolved unless specifically directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and an increased chance of cardiovascular events like heart attack or stroke, particularly with high‑dose or prolonged use.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, advanced kidney disease, or who are in the third trimester of pregnancy should avoid using Nurofen unless advised otherwise by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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